Gene description for Psmd14
Gene name proteasome (prosome, macropain) 26S subunit, non-ATPase, 14
Gene symbol Psmd14
Other names/aliases -
Species Rattus norvegicus
 Database cross references - Psmd14
ExoCarta ExoCarta_311078
Entrez Gene 311078
 Psmd14 identified in exosomes derived from the following tissue/cell type
Reticulocytes 21828046    
Reticulocytes 21828046    
 Gene ontology annotations for Psmd14
Molecular Function
    molecular_function GO:0003674 ND
    endopeptidase activator activity GO:0061133 ISO
    proteasome binding GO:0070628 ISO
Biological Process
    double-strand break repair via nonhomologous end joining GO:0006303 ISO
    protein K63-linked deubiquitination GO:0070536 ISO
    regulation of proteasomal protein catabolic process GO:0061136 ISO
    response to ethanol GO:0045471 IEP
    double-strand break repair via homologous recombination GO:0000724 ISO
    positive regulation of endopeptidase activity GO:0010950 ISO
Subcellular Localization
    proteasome complex GO:0000502 ISO
    extracellular exosome GO:0070062 ISO
    proteasome accessory complex GO:0022624 ISO
    proteasome regulatory particle, lid subcomplex GO:0008541 ISO
    nucleus GO:0005634 ISO
    cytosolic proteasome complex GO:0031597 IDA
 Experiment description of studies that identified Psmd14 in exosomes
1
Experiment ID 97
ISEV standards
EM
EV Biophysical techniques
TSG101|HSP90|HSC70
EV Cytosolic markers
MHCI
EV Membrane markers
EV Negative markers
EV Particle analysis
Identified molecule protein
Identification method Mass spectrometry [Orbitrap]
PubMed ID 21828046    
Organism Rattus norvegicus
Experiment description The proteo-lipidic composition of exosomes changes during reticulocyte maturation.
Authors Carayon K, Chaoui K, Ronzier E, Lazar I, Bertrand-Michel J, Roques V, Balor S, Terce F, Lopez A, Salome L, Joly E.
Journal name JBC
Publication year 2011
Sample Reticulocytes
Sample name Reticulocytes - D4 Rep 2
Isolation/purification methods Differential centrifugation
Ultracentrifugation
Sucrose density gradient
Flotation density 1.16-1.21 g/mL
Molecules identified in the study Protein
Lipids
Methods used in the study Mass spectrometry [QSTAR]
Mass spectrometry [Orbitrap]
Western blotting
2
Experiment ID 98
ISEV standards
EM
EV Biophysical techniques
TSG101|HSP90|HSC70
EV Cytosolic markers
MHCI
EV Membrane markers
EV Negative markers
EV Particle analysis
Identified molecule protein
Identification method Mass spectrometry [Orbitrap]
PubMed ID 21828046    
Organism Rattus norvegicus
Experiment description The proteo-lipidic composition of exosomes changes during reticulocyte maturation.
Authors Carayon K, Chaoui K, Ronzier E, Lazar I, Bertrand-Michel J, Roques V, Balor S, Terce F, Lopez A, Salome L, Joly E.
Journal name JBC
Publication year 2011
Sample Reticulocytes
Sample name Reticulocytes - D7 Rep 2
Isolation/purification methods Differential centrifugation
Ultracentrifugation
Sucrose density gradient
Flotation density 1.13-1.25 g/mL
Molecules identified in the study Protein
Lipids
Methods used in the study Mass spectrometry [QSTAR]
Mass spectrometry [Orbitrap]
Western blotting
 Protein-protein interactions for Psmd14
  Protein Interactor ExoCarta ID Identification method PubMed Species
No interactions are found.
 Pathways in which Psmd14 is involved
No pathways found





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