Gene description for Cadps2
Gene name Ca++-dependent secretion activator 2
Gene symbol Cadps2
Other names/aliases RGD1559440
Species Rattus norvegicus
 Database cross references - Cadps2
ExoCarta ExoCarta_312166
Vesiclepedia VP_312166
Entrez Gene 312166
 Cadps2 identified in sEVs derived from the following tissue/cell type
Pancreatic cancer cells 20124479    
Pancreatic cancer cells 20124479    
 Gene ontology annotations for Cadps2
Molecular Function
    lipid binding GO:0008289 IEA
Biological Process
    exocytosis GO:0006887 IBA
    cellular response to starvation GO:0009267 ISO
    protein transport GO:0015031 IEA
    synaptic vesicle priming GO:0016082 ISO
    synaptic vesicle priming GO:0016082 ISO
    positive regulation of exocytosis GO:0045921 IBA
    positive regulation of exocytosis GO:0045921 ISO
    hematopoietic stem cell homeostasis GO:0061484 ISO
    dense core granule exocytosis GO:1990504 IEA
Subcellular Localization
    nucleoplasm GO:0005654 IEA
    nucleoplasm GO:0005654 ISO
    centrosome GO:0005813 ISO
    cilium GO:0005929 ISO
    synaptic vesicle GO:0008021 ISO
    cytoplasmic vesicle membrane GO:0030659 IEA
    cytoplasmic vesicle GO:0031410 ISO
    ciliary basal body GO:0036064 ISO
    presynaptic membrane GO:0042734 ISO
    intracellular membrane-bounded organelle GO:0043231 ISO
    postsynaptic membrane GO:0045211 ISO
    parallel fiber to Purkinje cell synapse GO:0098688 ISO
    presynapse GO:0098793 ISO
    glutamatergic synapse GO:0098978 IBA
    glutamatergic synapse GO:0098978 ISO
 Experiment description of studies that identified Cadps2 in sEVs
1
Experiment ID 92
MISEV standards
Biophysical techniques
Enriched markers
Negative markers
Particle analysis
Identified molecule mrna
Identification method Microarray
PubMed ID 20124479    
Organism Rattus norvegicus
Experiment description Cell surface tetraspanin Tspan8 contributes to molecular pathways of exosome-induced endothelial cell activation.
Authors "Nazarenko I, Rana S, Baumann A, McAlear J, Hellwig A, Trendelenburg M, Lochnit G, Preissner KT, Zoller M."
Journal name CR
Publication year 2010
Sample Pancreatic cancer cells
Sample name AS
Isolation/purification methods Differential centrifugation
Sucrose density gradient
Flotation density 1.14-1.17 g/mL
Molecules identified in the study Protein
mRNA
Methods used in the study RT-PCR
Western blotting
RatRef-12 Microarray
FACS
Mass spectrometry [MALDI TOF]
2
Experiment ID 93
MISEV standards
Biophysical techniques
Enriched markers
Negative markers
Particle analysis
Identified molecule mrna
Identification method Microarray
PubMed ID 20124479    
Organism Rattus norvegicus
Experiment description Cell surface tetraspanin Tspan8 contributes to molecular pathways of exosome-induced endothelial cell activation.
Authors "Nazarenko I, Rana S, Baumann A, McAlear J, Hellwig A, Trendelenburg M, Lochnit G, Preissner KT, Zoller M."
Journal name CR
Publication year 2010
Sample Pancreatic cancer cells
Sample name AS-Tspan8
Isolation/purification methods Differential centrifugation
Sucrose density gradient
Flotation density 1.14-1.17 g/mL
Molecules identified in the study Protein
mRNA
Methods used in the study RT-PCR
Western blotting
 Protein-protein interactions for Cadps2
  Protein Interactor ExoCarta ID Identification method PubMed Species
No interactions are found.
 Pathways in which Cadps2 is involved
No pathways found





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