Gene description for Abcg2
Gene name	ATP-binding cassette, subfamily G (WHITE), member 2
Gene symbol	Abcg2
Other names/aliases	BCRP1
Species	Rattus norvegicus
Database cross references - Abcg2
ExoCarta	ExoCarta_312382
Vesiclepedia	VP_312382
Entrez Gene	312382
UniProt	Q80W57
Abcg2 identified in sEVs derived from the following tissue/cell type
Reticulocytes	21828046
Reticulocytes	21828046
Reticulocytes	21828046
Reticulocytes	21828046
Reticulocytes	21828046
Reticulocytes	21828046

Gene ontology annotations for Abcg2

Molecular Function     ATP binding GO:0005524 IEA     cytoskeletal protein binding GO:0008092 IPI     organic anion transmembrane transporter activity GO:0008514 IDA     ABC-type xenobiotic transporter activity GO:0008559 ISO     urate transmembrane transporter activity GO:0015143 ISO     urate transmembrane transporter activity GO:0015143 ISS     biotin transmembrane transporter activity GO:0015225 ISO     biotin transmembrane transporter activity GO:0015225 ISS     efflux transmembrane transporter activity GO:0015562 IBA     efflux transmembrane transporter activity GO:0015562 IDA     efflux transmembrane transporter activity GO:0015562 ISO     ATP hydrolysis activity GO:0016887 IEA     riboflavin transmembrane transporter activity GO:0032217 IBA     riboflavin transmembrane transporter activity GO:0032217 ISO     riboflavin transmembrane transporter activity GO:0032217 ISS     ATPase-coupled transmembrane transporter activity GO:0042626 IBA     ATPase-coupled transmembrane transporter activity GO:0042626 ISO     ATPase-coupled transmembrane transporter activity GO:0042626 ISS     ATPase-coupled transmembrane transporter activity GO:0042626 TAS     identical protein binding GO:0042802 ISO     protein homodimerization activity GO:0042803 ISO     amide transmembrane transporter activity GO:0042887 IDA     xenobiotic transmembrane transporter activity GO:0042910 IDA Biological Process     lipid transport GO:0006869 IEA     response to iron ion GO:0010039 IEP     organic anion transport GO:0015711 IDA     urate transport GO:0015747 IMP     biotin transport GO:0015878 ISO     biotin transport GO:0015878 ISS     riboflavin transport GO:0032218 ISO     riboflavin transport GO:0032218 ISS     response to lipopolysaccharide GO:0032496 IEP     response to insulin GO:0032868 IEP     urate metabolic process GO:0046415 ISO     response to folic acid GO:0051593 IEP     transmembrane transport GO:0055085 IBA     transmembrane transport GO:0055085 IMP     transmembrane transport GO:0055085 ISO     transmembrane transport GO:0055085 ISS     embryonic process involved in female pregnancy GO:0060136 IDA     protein-containing complex assembly GO:0065003 IDA     transepithelial transport GO:0070633 ISO     cellular response to estradiol stimulus GO:0071392 IEP     cellular response to dexamethasone stimulus GO:0071549 IEP     response to alcohol GO:0097305 IEP     renal urate salt excretion GO:0097744 IEP     renal urate salt excretion GO:0097744 ISO     export across plasma membrane GO:0140115 IDA     negative regulation of intestinal absorption GO:1904479 IMP     response to 2,3,7,8-tetrachlorodibenzodioxine GO:1904612 IEP     cellular detoxification GO:1990748 ISO     xenobiotic detoxification by transmembrane export across the plasma membrane GO:1990961 IDA     xenobiotic transport across blood-brain barrier GO:1990962 IC     xenobiotic transport across blood-brain barrier GO:1990962 ISO Subcellular Localization     nucleoplasm GO:0005654 ISO     plasma membrane GO:0005886 IBA     plasma membrane GO:0005886 ISO     apical plasma membrane GO:0016324 IDA     apical plasma membrane GO:0016324 ISO     brush border membrane GO:0031526 ISO     brush border membrane GO:0031526 ISS     mitochondrial membrane GO:0031966 IEA     membrane raft GO:0045121 ISO     membrane raft GO:0045121 ISS     external side of apical plasma membrane GO:0098591 IDA