Gene description for PI4KIIIalpha
Gene name Phosphatidylinositol 4-kinase III alpha
Gene symbol PI4KIIIalpha
Other names/aliases CG10260
DmelCG10260
EG:BACR7C10.2
PI4K
PI4KIII[[alpha]]
PI4KinaseIIIalpha
Pi4KIIIalpha
ZW-2
l(1)17-59
l(1)3Ah
l(1)VA722
l(1)zw2
stt4
zw-2
zw2
Species Drosophila melanogaster
 Database cross references - PI4KIIIalpha
ExoCarta ExoCarta_31247
Entrez Gene 31247
 PI4KIIIalpha identified in exosomes derived from the following tissue/cell type
Drosophila S2 cells 23035643    
 Gene ontology annotations for PI4KIIIalpha
Molecular Function
    1-phosphatidylinositol 4-kinase activity GO:0004430 NAS
Biological Process
    hippo signaling GO:0035329 IMP
    phosphatidylinositol-mediated signaling GO:0048015 IEA
    actin filament organization GO:0007015 IMP
    basement membrane organization GO:0071711 IMP
    establishment of cell polarity GO:0030010 IMP
    oocyte development GO:0048599 IMP
    phosphatidylinositol phosphorylation GO:0046854 IMP
    regulation of synaptic growth at neuromuscular junction GO:0008582 IMP
    oogenesis GO:0048477 IMP
    plasma membrane organization GO:0007009 IMP
    germarium-derived egg chamber formation GO:0007293 IMP
    phosphorylation GO:0016310 NAS
Subcellular Localization
    cellular_component GO:0005575 ND
 Experiment description of studies that identified PI4KIIIalpha in exosomes
1
Experiment ID 202
ISEV standards
IEM
EV Biophysical techniques
TSG10|RAB35
EV Cytosolic markers
FLOT2
EV Membrane markers
EV Negative markers
EV Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 23035643    
Organism Drosophila melanogaster
Experiment description Drosophila S2 cells secrete Wingless on exosome-like vesicles but the Wingless gradient forms independently of exosomes.
Authors Beckett K, Monier S, Palmer L, Alexandre C, Green H, Bonneil E, Raposo G, Thibault P, Borgne RL, Vincent JP.
Journal name Traffic
Publication year 2012
Sample Drosophila S2 cells
Sample name Normal-Drosophila S2 tub-Wg
Isolation/purification methods Filtration
Ultracentrifugation
Sucrose density gradient
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
 Protein-protein interactions for PI4KIIIalpha
  Protein Interactor ExoCarta ID Identification method PubMed Species
No interactions are found.
 Pathways in which PI4KIIIalpha is involved
No pathways found





Perform bioinformatics analysis of your extracellular vesicle data set using FunRich, a open access standalone tool. NEW UPDATED VERSION OF FunRich available for download (12/09/2016) from here