Gene description for Hsdl2
Gene name hydroxysteroid dehydrogenase like 2
Gene symbol Hsdl2
Other names/aliases RGD1305387
Species Rattus norvegicus
 Database cross references - Hsdl2
ExoCarta ExoCarta_313200
Vesiclepedia VP_313200
Entrez Gene 313200
UniProt Q4V8F9  
 Hsdl2 identified in sEVs derived from the following tissue/cell type
Adipocytes 25998041    
 Gene ontology annotations for Hsdl2
Molecular Function
    steroid dehydrogenase activity GO:0016229 ISO
    oxidoreductase activity GO:0016491 IEA
Biological Process
    cholesterol homeostasis GO:0042632 IEA
    cholesterol homeostasis GO:0042632 ISO
Subcellular Localization
    mitochondrion GO:0005739 IBA
    mitochondrion GO:0005739 IEA
    mitochondrion GO:0005739 ISO
    mitochondrion GO:0005739 ISS
    peroxisome GO:0005777 IEA
    peroxisome GO:0005777 ISO
 Experiment description of studies that identified Hsdl2 in sEVs
1
Experiment ID 225
MISEV standards
EM
Biophysical techniques
GAPDH|CD63
Enriched markers
Negative markers
NTA
Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 25998041    
Organism Rattus norvegicus
Experiment description Proteomic Analysis of Extracellular Vesicles Released by Adipocytes of Otsuka Long-Evans Tokushima Fatty (OLETF) Rats.
Authors "Lee JE, Moon PG, Lee IK, Baek MC"
Journal name Protein J
Publication year 2015
Sample Adipocytes
Sample name Adipocytes
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
Western blotting
 Protein-protein interactions for Hsdl2
  Protein Interactor ExoCarta ID Identification method PubMed Species
No interactions are found.
 Pathways in which Hsdl2 is involved
No pathways found





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