Gene description for Hp1bp3
Gene name heterochromatin protein 1, binding protein 3
Gene symbol Hp1bp3
Other names/aliases -
Species Rattus norvegicus
 Database cross references - Hp1bp3
ExoCarta ExoCarta_313647
Vesiclepedia VP_313647
Entrez Gene 313647
UniProt Q6P747  
 Hp1bp3 identified in sEVs derived from the following tissue/cell type
Reticulocytes 21828046    
 Gene ontology annotations for Hp1bp3
Molecular Function
    DNA binding GO:0003677 IBA
    DNA binding GO:0003677 IEA
    DNA binding GO:0003677 ISO
    DNA binding GO:0003677 ISS
    structural constituent of chromatin GO:0030527 IEA
    nucleosome binding GO:0031491 IBA
    nucleosome binding GO:0031491 IEA
    nucleosome binding GO:0031491 ISO
    nucleosome binding GO:0031491 ISS
Biological Process
    nucleosome assembly GO:0006334 IEA
    regulation of DNA-templated transcription GO:0006355 IEA
    regulation of DNA-templated transcription GO:0006355 ISO
    regulation of DNA-templated transcription GO:0006355 ISS
    regulation of cell population proliferation GO:0042127 IEA
    regulation of cell population proliferation GO:0042127 ISO
    regulation of cell population proliferation GO:0042127 ISS
    heterochromatin organization GO:0070828 IBA
    heterochromatin organization GO:0070828 IEA
    heterochromatin organization GO:0070828 ISO
    heterochromatin organization GO:0070828 ISS
    cellular response to hypoxia GO:0071456 IEA
    cellular response to hypoxia GO:0071456 ISO
    cellular response to hypoxia GO:0071456 ISS
    regulation of nucleus size GO:0097298 IEA
    regulation of nucleus size GO:0097298 ISO
    regulation of nucleus size GO:0097298 ISS
Subcellular Localization
    nucleosome GO:0000786 IEA
    nucleus GO:0005634 IBA
    nucleus GO:0005634 IEA
    nucleus GO:0005634 ISO
    nucleus GO:0005634 ISS
    chromosome GO:0005694 IBA
    chromosome GO:0005694 ISO
    chromosome GO:0005694 ISS
    nuclear speck GO:0016607 IEA
    nuclear speck GO:0016607 ISO
 Experiment description of studies that identified Hp1bp3 in sEVs
1
Experiment ID 96
MISEV standards
EM
Biophysical techniques
TSG101|HSP90|HSC70|MHCI
Enriched markers
Negative markers
Particle analysis
Identified molecule protein
Identification method Mass spectrometry [Orbitrap]
PubMed ID 21828046    
Organism Rattus norvegicus
Experiment description The proteo-lipidic composition of exosomes changes during reticulocyte maturation.
Authors "Carayon K, Chaoui K, Ronzier E, Lazar I, Bertrand-Michel J, Roques V, Balor S, Terce F, Lopez A, Salome L, Joly E."
Journal name JBC
Publication year 2011
Sample Reticulocytes
Sample name Reticulocytes - D2 Rep 2
Isolation/purification methods Differential centrifugation
Ultracentrifugation
Sucrose density gradient
Flotation density 1.16-1.21 g/mL
Molecules identified in the study Protein
Lipids
Methods used in the study Mass spectrometry [QSTAR]
Mass spectrometry [Orbitrap]
Western blotting
 Protein-protein interactions for Hp1bp3
  Protein Interactor ExoCarta ID Identification method PubMed Species
1 Dao  
Affinity Capture-MS Rattus norvegicus
2 Mib1  
Affinity Capture-MS Rattus norvegicus
3 Fbxo21  
Affinity Capture-MS Rattus norvegicus
View the network image/svg+xml
 Pathways in which Hp1bp3 is involved
No pathways found





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