Gene description for Hp1bp3
Gene name heterochromatin protein 1, binding protein 3
Gene symbol Hp1bp3
Other names/aliases -
Species Rattus norvegicus
 Database cross references - Hp1bp3
ExoCarta ExoCarta_313647
Entrez Gene 313647
UniProt Q6P747  
 Hp1bp3 identified in exosomes derived from the following tissue/cell type
Reticulocytes 21828046    
 Gene ontology annotations for Hp1bp3
Molecular Function
    DNA binding GO:0003677 ISS
    nucleosome binding GO:0031491 ISS
Biological Process
    nucleosome assembly GO:0006334 IEA
    cellular response to hypoxia GO:0071456 ISS
    heterochromatin organization GO:0070828 ISS
    regulation of nucleus size GO:0097298 ISS
    regulation of transcription, DNA-templated GO:0006355 ISS
    regulation of cell proliferation GO:0042127 ISS
Subcellular Localization
    chromosome GO:0005694 ISS
    nucleosome GO:0000786 IEA
    nucleus GO:0005634 ISS
 Experiment description of studies that identified Hp1bp3 in exosomes
1
Experiment ID 96
ISEV standards
EM
EV Biophysical techniques
TSG101|HSP90|HSC70
EV Cytosolic markers
MHCI
EV Membrane markers
EV Negative markers
EV Particle analysis
Identified molecule protein
Identification method Mass spectrometry [Orbitrap]
PubMed ID 21828046    
Organism Rattus norvegicus
Experiment description The proteo-lipidic composition of exosomes changes during reticulocyte maturation.
Authors Carayon K, Chaoui K, Ronzier E, Lazar I, Bertrand-Michel J, Roques V, Balor S, Terce F, Lopez A, Salome L, Joly E.
Journal name JBC
Publication year 2011
Sample Reticulocytes
Sample name Reticulocytes - D2 Rep 2
Isolation/purification methods Differential centrifugation
Ultracentrifugation
Sucrose density gradient
Flotation density 1.16-1.21 g/mL
Molecules identified in the study Protein
Lipids
Methods used in the study Mass spectrometry [QSTAR]
Mass spectrometry [Orbitrap]
Western blotting
 Protein-protein interactions for Hp1bp3
  Protein Interactor ExoCarta ID Identification method PubMed Species
No interactions are found.
 Pathways in which Hp1bp3 is involved
No pathways found





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