Gene description for Ddost
Gene name dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit (non-catalytic)
Gene symbol Ddost
Other names/aliases -
Species Rattus norvegicus
 Database cross references - Ddost
ExoCarta ExoCarta_313648
Entrez Gene 313648
UniProt Q641Y0  
 Ddost identified in exosomes derived from the following tissue/cell type
Adipocytes 25998041    
 Gene ontology annotations for Ddost
Molecular Function
    dolichyl-diphosphooligosaccharide-protein glycotransferase activity GO:0004579 ISO
    oligosaccharyl transferase activity GO:0004576 ISS
Biological Process
    protein N-linked glycosylation GO:0006487 ISO
    T cell activation GO:0042110 ISO
    protein N-linked glycosylation via asparagine GO:0018279 IEA
    protein glycosylation GO:0006486 ISS
    response to cytokine GO:0034097 ISO
Subcellular Localization
    protein complex GO:0043234 ISO
    integral component of membrane GO:0016021 IEA
    endoplasmic reticulum membrane GO:0005789 IEA
    membrane GO:0016020 ISO
    plasma membrane GO:0005886 TAS
    endoplasmic reticulum GO:0005783 ISO
    intracellular membrane-bounded organelle GO:0043231 ISO
    oligosaccharyltransferase complex GO:0008250 ISS
 Experiment description of studies that identified Ddost in exosomes
1
Experiment ID 225
ISEV standards
EM
EV Biophysical techniques
GAPDH
EV Cytosolic markers
CD63
EV Membrane markers
EV Negative markers
NTA
EV Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 25998041    
Organism Rattus norvegicus
Experiment description Proteomic Analysis of Extracellular Vesicles Released by Adipocytes of Otsuka Long-Evans Tokushima Fatty (OLETF) Rats.
Authors Lee JE, Moon PG, Lee IK, Baek MC
Journal name Protein J
Publication year 2015
Sample Adipocytes
Sample name Adipocytes
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
Western blotting
 Protein-protein interactions for Ddost
  Protein Interactor ExoCarta ID Identification method PubMed Species
No interactions are found.
 Pathways in which Ddost is involved
No pathways found





Perform bioinformatics analysis of your extracellular vesicle data set using FunRich, a open access standalone tool. NEW UPDATED VERSION OF FunRich available for download (12/09/2016) from here