Gene description for Lrpprc
Gene name leucine-rich pentatricopeptide repeat containing
Gene symbol Lrpprc
Other names/aliases Lrp157
Species Rattus norvegicus
 Database cross references - Lrpprc
ExoCarta ExoCarta_313867
Vesiclepedia VP_313867
Entrez Gene 313867
UniProt Q5SGE0  
 Lrpprc identified in sEVs derived from the following tissue/cell type
Adipocytes 25998041    
 Gene ontology annotations for Lrpprc
Molecular Function
    single-stranded DNA binding GO:0003697 IEA
    single-stranded DNA binding GO:0003697 ISO
    RNA binding GO:0003723 IEA
    RNA binding GO:0003723 ISO
    mRNA 3'-UTR binding GO:0003730 IBA
    ubiquitin protein ligase binding GO:0031625 IEA
    ubiquitin protein ligase binding GO:0031625 ISO
    beta-tubulin binding GO:0048487 IEA
    beta-tubulin binding GO:0048487 ISO
    beta-tubulin binding GO:0048487 ISS
    actin filament binding GO:0051015 ISO
    actin filament binding GO:0051015 ISS
Biological Process
    mitochondrial RNA catabolic process GO:0000957 IEA
    mitochondrial RNA catabolic process GO:0000957 ISO
    negative regulation of mitochondrial RNA catabolic process GO:0000961 IEA
    negative regulation of mitochondrial RNA catabolic process GO:0000961 ISO
    autophagy GO:0006914 IEA
    biological_process GO:0008150 ND
    mRNA transport GO:0051028 IEA
    regulation of mitochondrial translation GO:0070129 IBA
    regulation of mitochondrial translation GO:0070129 IEA
    regulation of mitochondrial translation GO:0070129 ISO
Subcellular Localization
    condensed nuclear chromosome GO:0000794 IEA
    condensed nuclear chromosome GO:0000794 ISO
    condensed nuclear chromosome GO:0000794 ISS
    nucleus GO:0005634 IBA
    nucleus GO:0005634 ISO
    nucleus GO:0005634 ISS
    nuclear inner membrane GO:0005637 IEA
    nuclear outer membrane GO:0005640 IEA
    nucleoplasm GO:0005654 IEA
    cytoplasm GO:0005737 ISO
    mitochondrion GO:0005739 IBA
    mitochondrion GO:0005739 ISO
    mitochondrion GO:0005739 ISS
    mitochondrial matrix GO:0005759 ISO
    cytoskeleton GO:0005856 ISO
    cytoskeleton GO:0005856 ISS
    microtubule GO:0005874 IEA
    microtubule GO:0005874 ISO
    mitochondrial nucleoid GO:0042645 IEA
    mitochondrial nucleoid GO:0042645 ISO
    perinuclear region of cytoplasm GO:0048471 IEA
    perinuclear region of cytoplasm GO:0048471 ISO
    perinuclear region of cytoplasm GO:0048471 ISS
    ribonucleoprotein complex GO:1990904 IEA
    ribonucleoprotein complex GO:1990904 ISO
 Experiment description of studies that identified Lrpprc in sEVs
1
Experiment ID 225
MISEV standards
✔
EM
Biophysical techniques
✔
GAPDH|CD63
Enriched markers
✘ Negative markers
✔
NTA
Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 25998041    
Organism Rattus norvegicus
Experiment description Proteomic Analysis of Extracellular Vesicles Released by Adipocytes of Otsuka Long-Evans Tokushima Fatty (OLETF) Rats.
Authors "Lee JE, Moon PG, Lee IK, Baek MC"
Journal name Protein J
Publication year 2015
Sample Adipocytes
Sample name Adipocytes
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
Western blotting
 Protein-protein interactions for Lrpprc
  Protein Interactor ExoCarta ID Identification method PubMed Species
No interactions are found.
 Pathways in which Lrpprc is involved
No pathways found





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