Gene description for Lrpprc
Gene name leucine-rich pentatricopeptide repeat containing
Gene symbol Lrpprc
Other names/aliases Lrp157
Species Rattus norvegicus
 Database cross references - Lrpprc
ExoCarta ExoCarta_313867
Entrez Gene 313867
UniProt Q5SGE0  
 Lrpprc identified in exosomes derived from the following tissue/cell type
Adipocytes 25998041    
 Gene ontology annotations for Lrpprc
Molecular Function
    single-stranded DNA binding GO:0003697 ISO
    DNA binding GO:0003677 IEA
    actin filament binding GO:0051015 ISS
    ubiquitin protein ligase binding GO:0031625 ISO
    RNA binding GO:0003723 ISO
    beta-tubulin binding GO:0048487 ISS
    molecular_function GO:0003674 ND
    poly(A) RNA binding GO:0044822 ISO
Biological Process
    transcription, DNA-templated GO:0006351 IEA
    negative regulation of mitochondrial RNA catabolic process GO:0000961 ISO
    regulation of mitochondrial translation GO:0070129 ISO
    mRNA transport GO:0051028 IEA
    regulation of transcription, DNA-templated GO:0006355 IEA
    biological_process GO:0008150 ND
Subcellular Localization
    nucleoplasm GO:0005654 IEA
    cytoplasm GO:0005737 ISO
    nucleus GO:0005634 ISS
    ribonucleoprotein complex GO:0030529 ISO
    nuclear inner membrane GO:0005637 IEA
    mitochondrial nucleoid GO:0042645 ISO
    mitochondrion GO:0005739 ISS
    membrane GO:0016020 ISO
    cellular_component GO:0005575 ND
    microtubule GO:0005874 ISO
    condensed nuclear chromosome GO:0000794 ISS
    cytoskeleton GO:0005856 ISS
    nuclear outer membrane GO:0005640 IEA
    perinuclear region of cytoplasm GO:0048471 ISS
 Experiment description of studies that identified Lrpprc in exosomes
1
Experiment ID 225
ISEV standards
✔
EM
EV Biophysical techniques
✔
GAPDH
EV Cytosolic markers
✔
CD63
EV Membrane markers
✘ EV Negative markers
✔
NTA
EV Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 25998041    
Organism Rattus norvegicus
Experiment description Proteomic Analysis of Extracellular Vesicles Released by Adipocytes of Otsuka Long-Evans Tokushima Fatty (OLETF) Rats.
Authors Lee JE, Moon PG, Lee IK, Baek MC
Journal name Protein J
Publication year 2015
Sample Adipocytes
Sample name Adipocytes
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
Western blotting
 Protein-protein interactions for Lrpprc
  Protein Interactor ExoCarta ID Identification method PubMed Species
No interactions are found.
 Pathways in which Lrpprc is involved
No pathways found





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