Gene description for Ap3d1
Gene name adaptor-related protein complex 3, delta 1 subunit
Gene symbol Ap3d1
Other names/aliases Ap3d
Species Rattus norvegicus
 Database cross references - Ap3d1
ExoCarta ExoCarta_314633
Vesiclepedia VP_314633
Entrez Gene 314633
 Ap3d1 identified in sEVs derived from the following tissue/cell type
Reticulocytes 21828046    
 Gene ontology annotations for Ap3d1
Molecular Function
    protein binding GO:0005515 IPI
Biological Process
    protein targeting GO:0006605 ISO
    protein targeting to vacuole GO:0006623 IBA
    intracellular protein transport GO:0006886 ISO
    Golgi to vacuole transport GO:0006896 IBA
    anterograde axonal transport GO:0008089 ISO
    synaptic vesicle budding from endosome GO:0016182 IBA
    synaptic vesicle budding from endosome GO:0016182 IDA
    synaptic vesicle budding from endosome GO:0016182 IMP
    synaptic vesicle budding from endosome GO:0016182 ISO
    antigen processing and presentation GO:0019882 ISO
    protein localization to organelle GO:0033365 ISO
    endosome to melanosome transport GO:0035646 ISO
    positive regulation of transcription by RNA polymerase II GO:0045944 ISO
    antigen processing and presentation, exogenous lipid antigen via MHC class Ib GO:0048007 ISO
    anterograde synaptic vesicle transport GO:0048490 IBA
    anterograde synaptic vesicle transport GO:0048490 ISO
    synaptic vesicle membrane organization GO:0048499 IBA
    synaptic vesicle membrane organization GO:0048499 ISO
    positive regulation of NK T cell differentiation GO:0051138 ISO
    protein localization to membrane GO:0072657 ISO
    neurotransmitter receptor transport, postsynaptic endosome to lysosome GO:0098943 IBA
    neurotransmitter receptor transport, postsynaptic endosome to lysosome GO:0098943 ISO
    vesicle-mediated transport in synapse GO:0099003 ISO
    zinc ion import into lysosome GO:0140916 ISO
Subcellular Localization
    endosome membrane GO:0010008 IBA
    endosome membrane GO:0010008 ISO
    AP-3 adaptor complex GO:0030123 IBA
    axon GO:0030424 ISO
    terminal bouton GO:0043195 IBA
    terminal bouton GO:0043195 ISO
    presynapse GO:0098793 ISO
    postsynapse GO:0098794 ISO
    presynaptic endosome GO:0098830 IBA
    presynaptic endosome GO:0098830 ISO
    glutamatergic synapse GO:0098978 ISO
    axon cytoplasm GO:1904115 IEA
 Experiment description of studies that identified Ap3d1 in sEVs
1
Experiment ID 98
MISEV standards
EM
Biophysical techniques
TSG101|HSP90|HSC70|MHCI
Enriched markers
Negative markers
Particle analysis
Identified molecule protein
Identification method Mass spectrometry [Orbitrap]
PubMed ID 21828046    
Organism Rattus norvegicus
Experiment description The proteo-lipidic composition of exosomes changes during reticulocyte maturation.
Authors "Carayon K, Chaoui K, Ronzier E, Lazar I, Bertrand-Michel J, Roques V, Balor S, Terce F, Lopez A, Salome L, Joly E."
Journal name JBC
Publication year 2011
Sample Reticulocytes
Sample name Reticulocytes - D7 Rep 2
Isolation/purification methods Differential centrifugation
Ultracentrifugation
Sucrose density gradient
Flotation density 1.13-1.25 g/mL
Molecules identified in the study Protein
Lipids
Methods used in the study Mass spectrometry [QSTAR]
Mass spectrometry [Orbitrap]
Western blotting
 Protein-protein interactions for Ap3d1
  Protein Interactor ExoCarta ID Identification method PubMed Species
1 Pi4k2a  
Affinity Capture-MS Mus musculus
View the network image/svg+xml
 Pathways in which Ap3d1 is involved
No pathways found





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