Gene description for Ndufa13
Gene name NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 13
Gene symbol Ndufa13
Other names/aliases RGD1565358
Species Rattus norvegicus
 Database cross references - Ndufa13
ExoCarta ExoCarta_314759
Entrez Gene 314759
 Ndufa13 identified in exosomes derived from the following tissue/cell type
Adipocytes 25998041    
 Gene ontology annotations for Ndufa13
Molecular Function
    NADH dehydrogenase (ubiquinone) activity GO:0008137 ISO
    NADH dehydrogenase activity GO:0003954 ISO
Biological Process
    reactive oxygen species metabolic process GO:0072593 ISO
    extrinsic apoptotic signaling pathway GO:0097191 ISO
    positive regulation of cysteine-type endopeptidase activity involved in apoptotic process GO:0043280 ISO
    cellular response to interferon-beta GO:0035458 ISO
    cellular response to retinoic acid GO:0071300 ISO
    negative regulation of cell growth GO:0030308 ISO
    protein import into mitochondrial inner membrane GO:0045039 ISO
    negative regulation of transcription, DNA-templated GO:0045892 ISO
    negative regulation of intrinsic apoptotic signaling pathway GO:2001243 ISO
    apoptotic signaling pathway GO:0097190 ISO
    positive regulation of protein catabolic process GO:0045732 ISO
Subcellular Localization
    extracellular exosome GO:0070062 ISO
    mitochondrial membrane GO:0031966 ISO
    mitochondrial inner membrane GO:0005743 ISO
    cytoplasm GO:0005737 ISO
    nucleoplasm GO:0005654 ISO
    nucleus GO:0005634 ISO
    mitochondrial respiratory chain GO:0005746 ISO
    mitochondrion GO:0005739 ISO
    mitochondrial respiratory chain complex I GO:0005747 ISO
 Experiment description of studies that identified Ndufa13 in exosomes
1
Experiment ID 225
ISEV standards
✔
EM
EV Biophysical techniques
✔
GAPDH
EV Cytosolic markers
✔
CD63
EV Membrane markers
✘ EV Negative markers
✔
NTA
EV Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 25998041    
Organism Rattus norvegicus
Experiment description Proteomic Analysis of Extracellular Vesicles Released by Adipocytes of Otsuka Long-Evans Tokushima Fatty (OLETF) Rats.
Authors Lee JE, Moon PG, Lee IK, Baek MC
Journal name Protein J
Publication year 2015
Sample Adipocytes
Sample name Adipocytes
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
Western blotting
 Protein-protein interactions for Ndufa13
  Protein Interactor ExoCarta ID Identification method PubMed Species
No interactions are found.
 Pathways in which Ndufa13 is involved
No pathways found





Perform bioinformatics analysis of your extracellular vesicle data set using FunRich, a open access standalone tool. NEW UPDATED VERSION OF FunRich available for download (12/09/2016) from here