Gene description for RGD1308195
Gene name similar to secreted Ly6/uPAR related protein 2
Gene symbol RGD1308195
Other names/aliases -
Species Rattus norvegicus
 Database cross references - RGD1308195
ExoCarta ExoCarta_315074
Vesiclepedia VP_315074
Entrez Gene 315074
 RGD1308195 identified in sEVs derived from the following tissue/cell type
Pancreatic cancer cells 20124479    
Pancreatic cancer cells 20124479    
 Gene ontology annotations for RGD1308195
Molecular Function
    acetylcholine receptor regulator activity GO:0030548 ISO
    acetylcholine receptor inhibitor activity GO:0030550 IBA
    acetylcholine receptor binding GO:0033130 IBA
    acetylcholine receptor binding GO:0033130 ISO
Biological Process
    keratinocyte proliferation GO:0043616 ISO
    acetylcholine receptor signaling pathway GO:0095500 IBA
    acetylcholine receptor signaling pathway GO:0095500 ISO
    regulation of neurotransmitter receptor activity GO:0099601 IBA
    regulation of neurotransmitter receptor activity GO:0099601 ISO
Subcellular Localization
    extracellular space GO:0005615 ISO
    plasma membrane GO:0005886 IBA
    synapse GO:0045202 IEA
 Experiment description of studies that identified RGD1308195 in sEVs
1
Experiment ID 92
MISEV standards
Biophysical techniques
Enriched markers
Negative markers
Particle analysis
Identified molecule mrna
Identification method Microarray
PubMed ID 20124479    
Organism Rattus norvegicus
Experiment description Cell surface tetraspanin Tspan8 contributes to molecular pathways of exosome-induced endothelial cell activation.
Authors "Nazarenko I, Rana S, Baumann A, McAlear J, Hellwig A, Trendelenburg M, Lochnit G, Preissner KT, Zoller M."
Journal name CR
Publication year 2010
Sample Pancreatic cancer cells
Sample name AS
Isolation/purification methods Differential centrifugation
Sucrose density gradient
Flotation density 1.14-1.17 g/mL
Molecules identified in the study Protein
mRNA
Methods used in the study RT-PCR
Western blotting
RatRef-12 Microarray
FACS
Mass spectrometry [MALDI TOF]
2
Experiment ID 93
MISEV standards
Biophysical techniques
Enriched markers
Negative markers
Particle analysis
Identified molecule mrna
Identification method Microarray
PubMed ID 20124479    
Organism Rattus norvegicus
Experiment description Cell surface tetraspanin Tspan8 contributes to molecular pathways of exosome-induced endothelial cell activation.
Authors "Nazarenko I, Rana S, Baumann A, McAlear J, Hellwig A, Trendelenburg M, Lochnit G, Preissner KT, Zoller M."
Journal name CR
Publication year 2010
Sample Pancreatic cancer cells
Sample name AS-Tspan8
Isolation/purification methods Differential centrifugation
Sucrose density gradient
Flotation density 1.14-1.17 g/mL
Molecules identified in the study Protein
mRNA
Methods used in the study RT-PCR
Western blotting
 Protein-protein interactions for RGD1308195
  Protein Interactor ExoCarta ID Identification method PubMed Species
No interactions are found.
 Pathways in which RGD1308195 is involved
No pathways found





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