Gene description for Tln2
Gene name talin 2
Gene symbol Tln2
Other names/aliases RGD1565416
Species Rattus norvegicus
 Database cross references - Tln2
ExoCarta ExoCarta_315776
Vesiclepedia VP_315776
Entrez Gene 315776
 Tln2 identified in sEVs derived from the following tissue/cell type
Adipocytes 25998041    
 Gene ontology annotations for Tln2
Molecular Function
    actin binding GO:0003779 IEA
    integrin binding GO:0005178 IBA
    structural constituent of cytoskeleton GO:0005200 IEA
    actin filament binding GO:0051015 IEA
Biological Process
    biological_process GO:0008150 ND
    actin cytoskeleton organization GO:0030036 IBA
    cell-cell adhesion GO:0098609 IBA
    presynaptic actin cytoskeleton organization GO:0099140 ISO
Subcellular Localization
    ruffle GO:0001726 IEA
    cytoplasm GO:0005737 IBA
    cytoskeleton GO:0005856 IEA
    plasma membrane GO:0005886 IBA
    fascia adherens GO:0005916 ISO
    focal adhesion GO:0005925 IBA
    synapse GO:0045202 ISO
    presynapse GO:0098793 IDA
 Experiment description of studies that identified Tln2 in sEVs
1
Experiment ID 225
MISEV standards
✔
EM
Biophysical techniques
✔
GAPDH|CD63
Enriched markers
✘ Negative markers
✔
NTA
Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 25998041    
Organism Rattus norvegicus
Experiment description Proteomic Analysis of Extracellular Vesicles Released by Adipocytes of Otsuka Long-Evans Tokushima Fatty (OLETF) Rats.
Authors "Lee JE, Moon PG, Lee IK, Baek MC"
Journal name Protein J
Publication year 2015
Sample Adipocytes
Sample name Adipocytes
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
Western blotting
 Protein-protein interactions for Tln2
  Protein Interactor ExoCarta ID Identification method PubMed Species
No interactions are found.
 Pathways in which Tln2 is involved
No pathways found





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