Gene description for Tln2
Gene name talin 2
Gene symbol Tln2
Other names/aliases RGD1565416
Species Rattus norvegicus
 Database cross references - Tln2
ExoCarta ExoCarta_315776
Entrez Gene 315776
 Tln2 identified in exosomes derived from the following tissue/cell type
Adipocytes 25998041    
 Gene ontology annotations for Tln2
Molecular Function
    insulin receptor binding GO:0005158 IEA
    structural constituent of cytoskeleton GO:0005200 IEA
    actin filament binding GO:0051015 IEA
    molecular_function GO:0003674 ND
Biological Process
    cell adhesion GO:0007155 IEA
    biological_process GO:0008150 ND
    cytoskeletal anchoring at plasma membrane GO:0007016 IEA
Subcellular Localization
    ruffle GO:0001726 IEA
    cytoskeleton GO:0005856 IEA
    fascia adherens GO:0005916 ISO
    synapse GO:0045202 ISO
    cellular_component GO:0005575 ND
    focal adhesion GO:0005925 ISO
 Experiment description of studies that identified Tln2 in exosomes
1
Experiment ID 225
ISEV standards
✔
EM
EV Biophysical techniques
✔
GAPDH
EV Cytosolic markers
✔
CD63
EV Membrane markers
✘ EV Negative markers
✔
NTA
EV Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 25998041    
Organism Rattus norvegicus
Experiment description Proteomic Analysis of Extracellular Vesicles Released by Adipocytes of Otsuka Long-Evans Tokushima Fatty (OLETF) Rats.
Authors Lee JE, Moon PG, Lee IK, Baek MC
Journal name Protein J
Publication year 2015
Sample Adipocytes
Sample name Adipocytes
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
Western blotting
 Protein-protein interactions for Tln2
  Protein Interactor ExoCarta ID Identification method PubMed Species
No interactions are found.
 Pathways in which Tln2 is involved
No pathways found





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