Gene description for MYH10
Gene name myosin, heavy chain 10, non-muscle
Gene symbol MYH10
Other names/aliases -
Species Bos taurus
 Database cross references - MYH10
ExoCarta ExoCarta_317655
Entrez Gene 317655
UniProt Q27991  
 MYH10 identified in exosomes derived from the following tissue/cell type
Milk 23459212    
 Gene ontology annotations for MYH10
Molecular Function
    microfilament motor activity GO:0000146 IEA
    ADP binding GO:0043531 IEA
    actin filament binding GO:0051015 IEA
    actin-dependent ATPase activity GO:0030898 IEA
    calmodulin binding GO:0005516 IEA
    ATP binding GO:0005524 IEA
Biological Process
    cell adhesion GO:0007155 IEA
    fourth ventricle development GO:0021592 IEA
    lateral ventricle development GO:0021670 IEA
    actin filament-based movement GO:0030048 IEA
    adult heart development GO:0007512 IEA
    neuromuscular process controlling balance GO:0050885 IEA
    plasma membrane repair GO:0001778 ISS
    regulation of cell shape GO:0008360 IEA
    cardiac myofibril assembly GO:0055003 IEA
    metabolic process GO:0008152 IEA
    ventricular cardiac muscle cell development GO:0055015 IEA
    cell proliferation GO:0008283 IEA
    exocytosis GO:0006887 ISS
    third ventricle development GO:0021678 IEA
    neuron migration GO:0001764 ISS
    in utero embryonic development GO:0001701 IEA
    nuclear migration GO:0007097 IEA
    retina development in camera-type eye GO:0060041 IEA
    axon guidance GO:0007411 IEA
    mitotic cytokinesis GO:0000281 IEA
    substrate-dependent cell migration, cell extension GO:0006930 ISS
    cerebellar Purkinje cell layer development GO:0021680 IEA
Subcellular Localization
    growth cone GO:0030426 IEA
    plasma membrane GO:0005886 IEA
    myosin II filament GO:0097513 IEA
    cleavage furrow GO:0032154 IEA
    dendritic spine GO:0043197 IEA
    stress fiber GO:0001725 ISS
    neuronal cell body GO:0043025 IEA
    cytoplasm GO:0005737 ISS
    myosin II complex GO:0016460 IEA
    spindle GO:0005819 IEA
    nucleus GO:0005634 IEA
    mitochondrion GO:0005739 IEA
    extracellular exosome GO:0070062 IEA
    axon GO:0030424 IEA
    neuromuscular junction GO:0031594 IEA
    lamellipodium GO:0030027 IEA
    midbody GO:0030496 IEA
    cell cortex GO:0005938 IEA
 Experiment description of studies that identified MYH10 in exosomes
1
Experiment ID 213
ISEV standards
EV Biophysical techniques
EV Cytosolic markers
EV Membrane markers
EV Negative markers
EV Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 23459212    
Organism Bos taurus
Experiment description Bovine milk proteome: Quantitative changes in normal milk exosomes, milk fat globule membranes and whey proteomes resulting from Staphylococcus aureus mastitis.
Authors Reinhardt TA, Sacco RE, Nonnecke BJ, Lippolis JD.
Journal name J Proteomics
Publication year 2013
Sample Milk
Sample name Staphylococcus aureus-infected-Milk
Isolation/purification methods Differential centrifugation
Ultracentrifugation
Filtration
Sucrose density gradient
FACS
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
 Protein-protein interactions for MYH10
  Protein Interactor ExoCarta ID Identification method PubMed Species
No interactions are found.



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