ExoCarta: Gene summary

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Gene description for USO1
Gene name	USO1 vesicle transport factor
Gene symbol	USO1
Other names/aliases	VDP
Species	Bos taurus
Database cross references - USO1
ExoCarta	ExoCarta_317724
Vesiclepedia	VP_317724
Entrez Gene	317724
UniProt	P41541
USO1 identified in sEVs derived from the following tissue/cell type
Milk	23459212

Gene ontology annotations for USO1

Molecular Function
	protein binding	GO:0005515	IEA
Biological Process
	intracellular protein transport	GO:0006886	IEA
	endoplasmic reticulum to Golgi vesicle-mediated transport	GO:0006888	IEA
	transcytosis	GO:0045056	IEA
	Golgi vesicle docking	GO:0048211	IEA
	vesicle fusion with Golgi apparatus	GO:0048280	IEA
Subcellular Localization
	Golgi membrane	GO:0000139	IEA
	cytoplasm	GO:0005737	IEA
	endoplasmic reticulum	GO:0005783	IEA
	Golgi stack	GO:0005795	IEA
	ER to Golgi transport vesicle membrane	GO:0012507	IEA

Experiment description of studies that identified USO1 in sEVs

Experiment ID

213

MISEV standards
✘	Biophysical techniques
✘	Enriched markers
✘	Negative markers
✘	Particle analysis

Identified molecule

protein

Identification method

Mass spectrometry

PubMed ID

23459212

Organism

Bos taurus

Experiment description

"Bovine milk proteome: Quantitative changes in normal milk exosomes, milk fat globule membranes and whey proteomes resulting from Staphylococcus aureus mastitis."

Authors

"Reinhardt TA, Sacco RE, Nonnecke BJ, Lippolis JD."

Journal name

J Proteomics

Publication year

2013

Sample

Milk

Sample name

Staphylococcus aureus-infected-Milk

Isolation/purification methods

Differential centrifugation
Ultracentrifugation
Filtration
Sucrose density gradient
FACS

Flotation density

Molecules identified in the study

Protein

Methods used in the study

Mass spectrometry

Protein-protein interactions for USO1

	Protein Interactor	ExoCarta ID	Identification method	PubMed	Species
No interactions are found.

Pathways in which USO1 is involved

Pathway	Evidence	Source
Asparagine N-linked glycosylation	IEA	Reactome
COPI-mediated anterograde transport	IEA	Reactome
COPII-mediated vesicle transport	IEA	Reactome
ER to Golgi Anterograde Transport	IEA	Reactome
Membrane Trafficking	IEA	Reactome
Metabolism of proteins	IEA	Reactome
Post-translational protein modification	IEA	Reactome
Transport to the Golgi and subsequent modification	IEA	Reactome
Vesicle-mediated transport	IEA	Reactome

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