Gene description for USO1
Gene name USO1 vesicle transport factor
Gene symbol USO1
Other names/aliases VDP
Species Bos taurus
 Database cross references - USO1
ExoCarta ExoCarta_317724
Entrez Gene 317724
UniProt P41541  
 USO1 identified in exosomes derived from the following tissue/cell type
Milk 23459212    
 Gene ontology annotations for USO1
Molecular Function
    poly(A) RNA binding GO:0044822 IEA
    identical protein binding GO:0042802 IPI
    protein transporter activity GO:0008565 ISS
Biological Process
    vesicle fusion with Golgi apparatus GO:0048280 IEA
    membrane fusion GO:0061025 IBA
    ER to Golgi vesicle-mediated transport GO:0006888 IBA
    transcytosis GO:0045056 IBA
    intracellular protein transport GO:0006886 ISS
    Golgi vesicle docking GO:0048211 IBA
    protein homooligomerization GO:0051260 IDA
    inter-Golgi cisterna vesicle-mediated transport GO:0048219 IMP
Subcellular Localization
    cytosol GO:0005829 ISS
    endoplasmic reticulum GO:0005783 IBA
    nucleolus GO:0005730 IEA
    perinuclear region of cytoplasm GO:0048471 ISS
    extrinsic component of Golgi membrane GO:0090498 IDA
    Golgi stack GO:0005795 IBA
    ER to Golgi transport vesicle membrane GO:0012507 IBA
 Experiment description of studies that identified USO1 in exosomes
1
Experiment ID 213
ISEV standards
✘ EV Biophysical techniques
✘ EV Cytosolic markers
✘ EV Membrane markers
✘ EV Negative markers
✘ EV Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 23459212    
Organism Bos taurus
Experiment description Bovine milk proteome: Quantitative changes in normal milk exosomes, milk fat globule membranes and whey proteomes resulting from Staphylococcus aureus mastitis.
Authors Reinhardt TA, Sacco RE, Nonnecke BJ, Lippolis JD.
Journal name J Proteomics
Publication year 2013
Sample Milk
Sample name Staphylococcus aureus-infected-Milk
Isolation/purification methods Differential centrifugation
Ultracentrifugation
Filtration
Sucrose density gradient
FACS
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
 Protein-protein interactions for USO1
  Protein Interactor ExoCarta ID Identification method PubMed Species
No interactions are found.
 Pathways in which USO1 is involved
PathwayEvidenceSource
Golgi Cisternae Pericentriolar Stack Reorganization IEA Reactome





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