Gene description for Hist2h2ac
Gene name histone cluster 2, H2ac
Gene symbol Hist2h2ac
Other names/aliases H2a-613b
Species Mus musculus
 Database cross references - Hist2h2ac
ExoCarta ExoCarta_319176
Entrez Gene 319176
UniProt Q64523  
 Hist2h2ac identified in exosomes derived from the following tissue/cell type
Oligodendrocytes 21136642    
 Gene ontology annotations for Hist2h2ac
Molecular Function
    protein heterodimerization activity GO:0046982 IEA
    DNA binding GO:0003677 IEA
Subcellular Localization
    extracellular exosome GO:0070062 ISO
    nucleus GO:0005634 ISO
    chromosome GO:0005694 IEA
    nucleosome GO:0000786 IEA
 Experiment description of studies that identified Hist2h2ac in exosomes
1
Experiment ID 33
ISEV standards
EM|IEM
EV Biophysical techniques
Alix|TSG101
EV Cytosolic markers
EV Membrane markers
EV Negative markers
EV Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 21136642    
Organism Mus musculus
Experiment description Oligodendrocytes secrete exosomes containing major myelin and stress-protective proteins: Trophic support for axons?
Authors Kramer-Albers EM, Bretz N, Tenzer S, Winterstein C, Mobius W, Berger H, Nave KA, Schild H, Trotter J
Journal name PROTEOMICS_CL
Publication year 2007
Sample Oligodendrocytes
Sample name Oligodendrocytes
Oli-neu
Isolation/purification methods Differential centrifugation
Sucrose density gradient
Flotation density 1.10-1.14 g/mL
Molecules identified in the study Protein
Methods used in the study Mass spectrometry [QTOF]
Western blotting
Immunoelectron Microscopy
 Protein-protein interactions for Hist2h2ac
  Protein Interactor ExoCarta ID Identification method PubMed Species
No interactions are found.



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