Gene description for Hist2h2ac
Gene name histone cluster 2, H2ac
Gene symbol Hist2h2ac
Other names/aliases H2a-613b
Species Mus musculus
 Database cross references - Hist2h2ac
ExoCarta ExoCarta_319176
Entrez Gene 319176
UniProt Q64523  
 Hist2h2ac identified in exosomes derived from the following tissue/cell type
Oligodendrocytes 21136642    
 Gene ontology annotations for Hist2h2ac
Molecular Function
    protein heterodimerization activity GO:0046982 IEA
    DNA binding GO:0003677 IEA
Subcellular Localization
    extracellular exosome GO:0070062 ISO
    nucleus GO:0005634 ISO
    chromosome GO:0005694 IEA
    nucleosome GO:0000786 IEA
 Experiment description of studies that identified Hist2h2ac in exosomes
1
Experiment ID 33
ISEV standards
✔
EM|IEM
EV Biophysical techniques
✔
Alix|TSG101
EV Cytosolic markers
✘ EV Membrane markers
✘ EV Negative markers
✘ EV Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 21136642    
Organism Mus musculus
Experiment description Oligodendrocytes secrete exosomes containing major myelin and stress-protective proteins: Trophic support for axons?
Authors Kramer-Albers EM, Bretz N, Tenzer S, Winterstein C, Mobius W, Berger H, Nave KA, Schild H, Trotter J
Journal name PROTEOMICS_CL
Publication year 2007
Sample Oligodendrocytes
Sample name Oligodendrocytes
Oli-neu
Isolation/purification methods Differential centrifugation
Sucrose density gradient
Flotation density 1.10-1.14 g/mL
Molecules identified in the study Protein
Methods used in the study Mass spectrometry [QTOF]
Western blotting
Immunoelectron Microscopy
 Protein-protein interactions for Hist2h2ac
  Protein Interactor ExoCarta ID Identification method PubMed Species
No interactions are found.



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