Gene description for Vwc2l
Gene name von Willebrand factor C domain-containing protein 2-like
Gene symbol Vwc2l
Other names/aliases A830006F12Rik
Brl
Species Mus musculus
 Database cross references - Vwc2l
ExoCarta ExoCarta_320460
Entrez Gene 320460
UniProt Q505H4  
 Vwc2l identified in exosomes derived from the following tissue/cell type
Mast cells 17486113    
 Gene ontology annotations for Vwc2l
Molecular Function
    molecular_function GO:0003674 ND
Biological Process
    negative regulation of BMP signaling pathway GO:0030514 IGI
    positive regulation of neuron differentiation GO:0045666 IDA
    multicellular organismal development GO:0007275 IEA
Subcellular Localization
    extracellular space GO:0005615 IDA
    alpha-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid selective glutamate receptor complex GO:0032281 IDA
    cell junction GO:0030054 IEA
    extracellular region GO:0005576 IEA
    synapse GO:0045202 IEA
 Experiment description of studies that identified Vwc2l in exosomes
1
Experiment ID 15
ISEV standards
EM
EV Biophysical techniques
EV Cytosolic markers
CD63
EV Membrane markers
EV Negative markers
EV Particle analysis
Identified molecule mrna
Identification method Microarray
PubMed ID 17486113    
Organism Mus musculus
Homo sapiens
Experiment description Exosome-mediated transfer of mRNAs and microRNAs is a novel mechanism of genetic exchange between cells.
Authors Valadi H, Ekstrom K, Bossios A, Sjostrand M, Lee JJ, Lotvall JO
Journal name NCB
Publication year 2007
Sample Mast cells
Sample name MC9
Bone marrow-derived mast cells
HMC-1
Isolation/purification methods Filtration
Ultracentrifugation
Sucrose density gradient
Flotation density 1.11-1.21 g/mL
Molecules identified in the study Protein
mRNA
miRNA
Methods used in the study Mass spectrometry [MALDI TOF]
Western blotting
Microarray
miRCURY LNA Array
 Protein-protein interactions for Vwc2l
  Protein Interactor ExoCarta ID Identification method PubMed Species
No interactions are found.
 Pathways in which Vwc2l is involved
No pathways found





Perform bioinformatics analysis of your extracellular vesicle data set using FunRich, a open access standalone tool. NEW UPDATED VERSION OF FunRich available for download (12/09/2016) from here