Gene description for Xpnpep3
Gene name X-prolyl aminopeptidase (aminopeptidase P) 3, putative
Gene symbol Xpnpep3
Other names/aliases APP3
E430012M05Rik
Species Mus musculus
 Database cross references - Xpnpep3
ExoCarta ExoCarta_321003
Vesiclepedia VP_321003
Entrez Gene 321003
UniProt B7ZMP1  
 Xpnpep3 identified in sEVs derived from the following tissue/cell type
Fibroblasts 23260141    
 Gene ontology annotations for Xpnpep3
Molecular Function
    aminopeptidase activity GO:0004177 IBA
    aminopeptidase activity GO:0004177 ISO
    manganese ion binding GO:0030145 IEA
    manganese ion binding GO:0030145 ISO
    protein homodimerization activity GO:0042803 IEA
    protein homodimerization activity GO:0042803 ISO
    metalloaminopeptidase activity GO:0070006 IEA
    metalloaminopeptidase activity GO:0070006 ISO
Biological Process
    glomerular filtration GO:0003094 ISO
    proteolysis GO:0006508 IBA
    proteolysis GO:0006508 ISO
    protein processing GO:0016485 ISO
Subcellular Localization
    cytoplasm GO:0005737 ISO
    mitochondrion GO:0005739 HDA
    mitochondrion GO:0005739 IBA
    mitochondrion GO:0005739 IDA
    mitochondrion GO:0005739 ISO
    cytosol GO:0005829 IEA
    cytosol GO:0005829 ISO
 Experiment description of studies that identified Xpnpep3 in sEVs
1
Experiment ID 210
MISEV standards
EM
Biophysical techniques
CD81|FLOT1
Enriched markers
Negative markers
Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 23260141    
Organism Mus musculus
Experiment description Exosomes Mediate Stromal Mobilization of Autocrine Wnt-PCP Signaling in Breast Cancer Cell Migration.
Authors "Luga V, Zhang L, Viloria-Petit AM, Ogunjimi AA, Inanlou MR, Chiu E, Buchanan M, Hosein AN, Basik M, Wrana JL."
Journal name Cell
Publication year 2012
Sample Fibroblasts
Sample name Normal-Fibroblasts (L cells)
Isolation/purification methods Differential centrifugation
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
 Protein-protein interactions for Xpnpep3
  Protein Interactor ExoCarta ID Identification method PubMed Species
No interactions are found.
 Pathways in which Xpnpep3 is involved
No pathways found





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