Gene description for Serac1
Gene name serine active site containing 1
Gene symbol Serac1
Other names/aliases 4930511N22Rik
D17Ertd141e
Species Mus musculus
 Database cross references - Serac1
ExoCarta ExoCarta_321007
Vesiclepedia VP_321007
Entrez Gene 321007
UniProt Q3U213  
 Serac1 identified in sEVs derived from the following tissue/cell type
Fibroblasts 23260141    
 Gene ontology annotations for Serac1
Biological Process
    phospholipid biosynthetic process GO:0008654 IEA
    extracellular matrix organization GO:0030198 IDA
    intracellular cholesterol transport GO:0032367 IEA
    intracellular cholesterol transport GO:0032367 ISO
    phosphatidylglycerol acyl-chain remodeling GO:0036148 IEA
    phosphatidylglycerol acyl-chain remodeling GO:0036148 ISO
Subcellular Localization
    mitochondrion GO:0005739 ISO
    mitochondrial outer membrane GO:0005741 IDA
    endoplasmic reticulum GO:0005783 ISO
    endoplasmic reticulum membrane GO:0005789 IDA
    extracellular matrix GO:0031012 IDA
    mitochondria-associated endoplasmic reticulum membrane contact site GO:0044233 IEA
    mitochondria-associated endoplasmic reticulum membrane contact site GO:0044233 ISO
 Experiment description of studies that identified Serac1 in sEVs
1
Experiment ID 210
MISEV standards
EM
Biophysical techniques
CD81|FLOT1
Enriched markers
Negative markers
Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 23260141    
Organism Mus musculus
Experiment description Exosomes Mediate Stromal Mobilization of Autocrine Wnt-PCP Signaling in Breast Cancer Cell Migration.
Authors "Luga V, Zhang L, Viloria-Petit AM, Ogunjimi AA, Inanlou MR, Chiu E, Buchanan M, Hosein AN, Basik M, Wrana JL."
Journal name Cell
Publication year 2012
Sample Fibroblasts
Sample name Normal-Fibroblasts (L cells)
Isolation/purification methods Differential centrifugation
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
 Protein-protein interactions for Serac1
  Protein Interactor ExoCarta ID Identification method PubMed Species
1 Fancd2  
Affinity Capture-MS Mus musculus
View the network image/svg+xml
 Pathways in which Serac1 is involved
No pathways found





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