Gene description for Serac1
Gene name serine active site containing 1
Gene symbol Serac1
Other names/aliases 4930511N22Rik
Species Mus musculus
 Database cross references - Serac1
ExoCarta ExoCarta_321007
Entrez Gene 321007
UniProt Q3U213  
 Serac1 identified in exosomes derived from the following tissue/cell type
Fibroblasts 23260141    
 Gene ontology annotations for Serac1
Molecular Function
    hydrolase activity, acting on ester bonds GO:0016788 IEA
Biological Process
    GPI anchor metabolic process GO:0006505 IEA
    extracellular matrix organization GO:0030198 IDA
    intracellular protein transport GO:0006886 IEA
    lipid metabolic process GO:0006629 IEA
    phospholipid biosynthetic process GO:0008654 IEA
Subcellular Localization
    mitochondrion GO:0005739 ISO
    membrane GO:0016020 IEA
    cytoplasm GO:0005737 ISO
    proteinaceous extracellular matrix GO:0005578 IDA
    endoplasmic reticulum GO:0005783 IEA
    integral component of membrane GO:0016021 IEA
    nucleoplasm GO:0005654 ISO
 Experiment description of studies that identified Serac1 in exosomes
Experiment ID 210
ISEV standards
EV Biophysical techniques
EV Cytosolic markers
EV Membrane markers
EV Negative markers
EV Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 23260141    
Organism Mus musculus
Experiment description Exosomes Mediate Stromal Mobilization of Autocrine Wnt-PCP Signaling in Breast Cancer Cell Migration.
Authors Luga V, Zhang L, Viloria-Petit AM, Ogunjimi AA, Inanlou MR, Chiu E, Buchanan M, Hosein AN, Basik M, Wrana JL.
Journal name Cell
Publication year 2012
Sample Fibroblasts
Sample name Normal-Fibroblasts (L cells)
Isolation/purification methods Differential centrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
 Protein-protein interactions for Serac1
  Protein Interactor ExoCarta ID Identification method PubMed Species
No interactions are found.
 Pathways in which Serac1 is involved
No pathways found

Perform bioinformatics analysis of your extracellular vesicle data set using FunRich, a open access standalone tool. NEW UPDATED VERSION OF FunRich available for download (12/09/2016) from here