Gene description for Ahcy13
Gene name Adenosylhomocysteinase at 13
Gene symbol Ahcy13
Other names/aliases CG11654
DmelCG11654
SAHH
ahcY
Species Drosophila melanogaster
 Database cross references - Ahcy13
ExoCarta ExoCarta_32471
Entrez Gene 32471
UniProt Q27580  
 Ahcy13 identified in exosomes derived from the following tissue/cell type
Drosophila S2 cells 23035643    
 Gene ontology annotations for Ahcy13
Molecular Function
    adenosylhomocysteinase activity GO:0004013 NAS
Biological Process
    one-carbon metabolic process GO:0006730 IEA
 Experiment description of studies that identified Ahcy13 in exosomes
1
Experiment ID 202
ISEV standards
✔
IEM
EV Biophysical techniques
✔
TSG10|RAB35
EV Cytosolic markers
✔
FLOT2
EV Membrane markers
✘ EV Negative markers
✘ EV Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 23035643    
Organism Drosophila melanogaster
Experiment description Drosophila S2 cells secrete Wingless on exosome-like vesicles but the Wingless gradient forms independently of exosomes.
Authors Beckett K, Monier S, Palmer L, Alexandre C, Green H, Bonneil E, Raposo G, Thibault P, Borgne RL, Vincent JP.
Journal name Traffic
Publication year 2012
Sample Drosophila S2 cells
Sample name Normal-Drosophila S2 tub-Wg
Isolation/purification methods Filtration
Ultracentrifugation
Sucrose density gradient
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
 Protein-protein interactions for Ahcy13
  Protein Interactor ExoCarta ID Identification method PubMed Species
No interactions are found.
 Pathways in which Ahcy13 is involved
PathwayEvidenceSource
Methylation IEA Reactome
Sulfur amino acid metabolism IEA Reactome





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