Gene description for SNW1
Gene name SNW domain containing 1
Gene symbol SNW1
Other names/aliases NCOA-62
Species Bos taurus
 Database cross references - SNW1
ExoCarta ExoCarta_326578
Entrez Gene 326578
UniProt Q1JQE0  
 SNW1 identified in exosomes derived from the following tissue/cell type
Milk 23459212    
 Gene ontology annotations for SNW1
Molecular Function
    retinoic acid receptor binding GO:0042974 ISS
    transcription coactivator activity GO:0003713 ISS
    SMAD binding GO:0046332 ISS
    nuclear hormone receptor binding GO:0035257 ISS
    poly(A) RNA binding GO:0044822 IEA
    vitamin D receptor binding GO:0042809 ISS
    Notch binding GO:0005112 IEA
    transcription corepressor activity GO:0003714 ISS
Biological Process
    intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator GO:0042771 ISS
    positive regulation of vitamin D receptor signaling pathway GO:0070564 IEA
    regulation of retinoic acid receptor signaling pathway GO:0048385 ISS
    transcription, DNA-templated GO:0006351 IEA
    positive regulation by host of viral transcription GO:0043923 IEA
    positive regulation of histone H3-K4 methylation GO:0051571 ISS
    positive regulation of transforming growth factor beta receptor signaling pathway GO:0030511 ISS
    positive regulation of mRNA splicing, via spliceosome GO:0048026 ISS
    positive regulation of transcription from RNA polymerase II promoter GO:0045944 ISS
    positive regulation of neurogenesis GO:0050769 ISS
    retinoic acid receptor signaling pathway GO:0048384 ISS
    regulation of vitamin D receptor signaling pathway GO:0070562 ISS
    negative regulation of transcription from RNA polymerase II promoter GO:0000122 ISS
    cellular response to retinoic acid GO:0071300 IEA
    mRNA splicing, via spliceosome GO:0000398 IEA
Subcellular Localization
    SMAD3-SMAD4 protein complex GO:0071146 ISS
    catalytic step 2 spliceosome GO:0071013 IEA
    nuclear matrix GO:0016363 ISS
    positive transcription elongation factor complex b GO:0008024 ISS
 Experiment description of studies that identified SNW1 in exosomes
Experiment ID 213
ISEV standards
EV Biophysical techniques
EV Cytosolic markers
EV Membrane markers
EV Negative markers
EV Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 23459212    
Organism Bos taurus
Experiment description Bovine milk proteome: Quantitative changes in normal milk exosomes, milk fat globule membranes and whey proteomes resulting from Staphylococcus aureus mastitis.
Authors Reinhardt TA, Sacco RE, Nonnecke BJ, Lippolis JD.
Journal name J Proteomics
Publication year 2013
Sample Milk
Sample name Staphylococcus aureus-infected-Milk
Isolation/purification methods Differential centrifugation
Sucrose density gradient
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
 Protein-protein interactions for SNW1
  Protein Interactor ExoCarta ID Identification method PubMed Species
No interactions are found.

Perform bioinformatics analysis of your extracellular vesicle data set using FunRich, a open access standalone tool. NEW UPDATED VERSION OF FunRich available for download (12/09/2016) from here