Gene description for TBCA
Gene name tubulin folding cofactor A
Gene symbol TBCA
Other names/aliases -
Species Bos taurus
 Database cross references - TBCA
ExoCarta ExoCarta_327683
Entrez Gene 327683
UniProt P48427  
 TBCA identified in exosomes derived from the following tissue/cell type
Milk 23459212    
 Gene ontology annotations for TBCA
Molecular Function
    unfolded protein binding GO:0051082 IEA
    tubulin binding GO:0015631 IEA
    poly(A) RNA binding GO:0044822 IEA
Biological Process
    post-chaperonin tubulin folding pathway GO:0007023 TAS
    tubulin complex assembly GO:0007021 IEA
Subcellular Localization
    extracellular exosome GO:0070062 IEA
    cytosol GO:0005829 TAS
    microtubule GO:0005874 IEA
    nucleolus GO:0005730 IEA
 Experiment description of studies that identified TBCA in exosomes
1
Experiment ID 213
ISEV standards
✘ EV Biophysical techniques
✘ EV Cytosolic markers
✘ EV Membrane markers
✘ EV Negative markers
✘ EV Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 23459212    
Organism Bos taurus
Experiment description Bovine milk proteome: Quantitative changes in normal milk exosomes, milk fat globule membranes and whey proteomes resulting from Staphylococcus aureus mastitis.
Authors Reinhardt TA, Sacco RE, Nonnecke BJ, Lippolis JD.
Journal name J Proteomics
Publication year 2013
Sample Milk
Sample name Staphylococcus aureus-infected-Milk
Isolation/purification methods Differential centrifugation
Ultracentrifugation
Filtration
Sucrose density gradient
FACS
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
 Protein-protein interactions for TBCA
  Protein Interactor ExoCarta ID Identification method PubMed Species
No interactions are found.
 Pathways in which TBCA is involved
PathwayEvidenceSource
Post-chaperonin tubulin folding pathway IEA Reactome





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