Gene description for ANXA6
Gene name annexin A6
Gene symbol ANXA6
Other names/aliases -
Species Bos taurus
 Database cross references - ANXA6
ExoCarta ExoCarta_327685
Vesiclepedia VP_327685
Entrez Gene 327685
UniProt P79134  
 ANXA6 identified in sEVs derived from the following tissue/cell type
Milk 23459212    
 Gene ontology annotations for ANXA6
Molecular Function
    phosphatidylserine binding GO:0001786 IEA
    calcium channel activity GO:0005262 IEA
    calcium ion binding GO:0005509 IEA
    GTP binding GO:0005525 IEA
    calcium-dependent phospholipid binding GO:0005544 IEA
    ligand-gated monoatomic ion channel activity GO:0015276 IEA
    cholesterol binding GO:0015485 IEA
    chondroitin sulfate binding GO:0035374 IEA
    actin filament binding GO:0051015 IEA
Biological Process
    neural crest cell migration GO:0001755 IEA
    plasma membrane repair GO:0001778 IEA
    growth plate cartilage chondrocyte differentiation GO:0003418 IEA
    regulation of muscle contraction GO:0006937 IEA
    negative regulation of sequestering of calcium ion GO:0051283 IEA
    mitochondrial calcium ion homeostasis GO:0051560 IEA
    apoptotic signaling pathway GO:0097190 IEA
Subcellular Localization
    cytoplasm GO:0005737 IEA
    focal adhesion GO:0005925 IEA
 Experiment description of studies that identified ANXA6 in sEVs
1
Experiment ID 213
MISEV standards
Biophysical techniques
Enriched markers
Negative markers
Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 23459212    
Organism Bos taurus
Experiment description "Bovine milk proteome: Quantitative changes in normal milk exosomes, milk fat globule membranes and whey proteomes resulting from Staphylococcus aureus mastitis."
Authors "Reinhardt TA, Sacco RE, Nonnecke BJ, Lippolis JD."
Journal name J Proteomics
Publication year 2013
Sample Milk
Sample name Staphylococcus aureus-infected-Milk
Isolation/purification methods Differential centrifugation
Ultracentrifugation
Filtration
Sucrose density gradient
FACS
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
 Protein-protein interactions for ANXA6
  Protein Interactor ExoCarta ID Identification method PubMed Species
No interactions are found.
 Pathways in which ANXA6 is involved
No pathways found





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