Gene description for EIF2S1
Gene name eukaryotic translation initiation factor 2, subunit 1 alpha, 35kDa
Gene symbol EIF2S1
Other names/aliases -
Species Bos taurus
 Database cross references - EIF2S1
ExoCarta ExoCarta_327694
Entrez Gene 327694
UniProt P68102  
 EIF2S1 identified in exosomes derived from the following tissue/cell type
Milk 23459212    
 Gene ontology annotations for EIF2S1
Molecular Function
    ribosome binding GO:0043022 ISS
    translation initiation factor activity GO:0003743 ISS
    poly(A) RNA binding GO:0044822 IBA
Biological Process
    regulation of translational initiation in response to stress GO:0043558 ISS
    translation GO:0006412 ISS
    protein autophosphorylation GO:0046777 IEA
    translational initiation GO:0006413 IBA
Subcellular Localization
    eukaryotic translation initiation factor 2B complex GO:0005851 ISS
    eukaryotic translation initiation factor 2 complex GO:0005850 IBA
    ribosome GO:0005840 IBA
    membrane GO:0016020 IEA
    extracellular exosome GO:0070062 IEA
    multi-eIF complex GO:0043614 IBA
    cytoplasmic stress granule GO:0010494 ISS
    eukaryotic 48S preinitiation complex GO:0033290 IBA
    nucleus GO:0005634 ISS
    cytoplasm GO:0005737 ISS
 Experiment description of studies that identified EIF2S1 in exosomes
Experiment ID 213
ISEV standards
EV Biophysical techniques
EV Cytosolic markers
EV Membrane markers
EV Negative markers
EV Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 23459212    
Organism Bos taurus
Experiment description Bovine milk proteome: Quantitative changes in normal milk exosomes, milk fat globule membranes and whey proteomes resulting from Staphylococcus aureus mastitis.
Authors Reinhardt TA, Sacco RE, Nonnecke BJ, Lippolis JD.
Journal name J Proteomics
Publication year 2013
Sample Milk
Sample name Staphylococcus aureus-infected-Milk
Isolation/purification methods Differential centrifugation
Sucrose density gradient
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
 Protein-protein interactions for EIF2S1
  Protein Interactor ExoCarta ID Identification method PubMed Species
No interactions are found.

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