Gene description for Ppp1r12b
Gene name protein phosphatase 1, regulatory (inhibitor) subunit 12B
Gene symbol Ppp1r12b
Other names/aliases 1810037O03Rik
9530009M10Rik
AI132431
Mypt2
Species Mus musculus
 Database cross references - Ppp1r12b
ExoCarta ExoCarta_329251
Vesiclepedia VP_329251
Entrez Gene 329251
UniProt Q8BG95  
 Ppp1r12b identified in sEVs derived from the following tissue/cell type
Fibroblasts 23260141    
 Gene ontology annotations for Ppp1r12b
Molecular Function
    enzyme inhibitor activity GO:0004857 IBA
    myosin phosphatase regulator activity GO:0017020 IBA
    phosphatase regulator activity GO:0019208 IEA
    protein kinase binding GO:0019901 IEA
Biological Process
    signal transduction GO:0007165 IEA
    neuron projection morphogenesis GO:0048812 IBA
Subcellular Localization
    stress fiber GO:0001725 IEA
    cytoplasm GO:0005737 IBA
    Z disc GO:0030018 IBA
    Z disc GO:0030018 IDA
    A band GO:0031672 IBA
    A band GO:0031672 IDA
 Experiment description of studies that identified Ppp1r12b in sEVs
1
Experiment ID 210
MISEV standards
EM
Biophysical techniques
CD81|FLOT1
Enriched markers
Negative markers
Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 23260141    
Organism Mus musculus
Experiment description Exosomes Mediate Stromal Mobilization of Autocrine Wnt-PCP Signaling in Breast Cancer Cell Migration.
Authors "Luga V, Zhang L, Viloria-Petit AM, Ogunjimi AA, Inanlou MR, Chiu E, Buchanan M, Hosein AN, Basik M, Wrana JL."
Journal name Cell
Publication year 2012
Sample Fibroblasts
Sample name Normal-Fibroblasts (L cells)
Isolation/purification methods Differential centrifugation
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
 Protein-protein interactions for Ppp1r12b
  Protein Interactor ExoCarta ID Identification method PubMed Species
1 Ppp1r12c  
Co-fractionation Mus musculus
2 Kctd13  
Affinity Capture-MS Mus musculus
3 Nebl  
Co-fractionation Mus musculus
4 Acad10  
Co-fractionation Mus musculus
5 Rin1  
Co-fractionation Mus musculus
View the network image/svg+xml
 Pathways in which Ppp1r12b is involved
No pathways found





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