Gene description for Cdc42
Gene name	CG12530 gene product from transcript CG12530-RC
Gene symbol	Cdc42
Other names/aliases	CDC42 CG12530 Cdc42Dm D-CDC42 D-Cdc42 D-cdc42 DCDC42 DCdc42 Dcdc42 Dm Cdc42 DmCDC42 Dmcdc42 DmelCG12530 P40793 cdc42
Species	Drosophila melanogaster
Database cross references - Cdc42
ExoCarta	ExoCarta_32981
Vesiclepedia	VP_32981
Entrez Gene	32981
UniProt	P40793
Cdc42 identified in exosomes derived from the following tissue/cell type
Drosophila S2 cells	23035643

Gene ontology annotations for Cdc42

Molecular Function     GTPase activity GO:0003924 IDA     protein binding GO:0005515 IPI     protein kinase binding GO:0019901 IPI     GTPase activating protein binding GO:0032794 IPI Biological Process     phagocytosis GO:0006909 IMP     actin filament organization GO:0007015 IMP     Rho protein signal transduction GO:0007266 IGI     neuromuscular synaptic transmission GO:0007274 IGI     spermatid development GO:0007286 IMP     border follicle cell migration GO:0007298 IMP     cellularization GO:0007349 TAS     dorsal closure GO:0007391 IMP     dorsal closure GO:0007391 TAS     axonogenesis GO:0007409 TAS     axon guidance GO:0007411 IMP     motor neuron axon guidance GO:0008045 IMP     regulation of cell shape GO:0008360 IMP     regulation of synaptic assembly at neuromuscular junction GO:0008582 IDA     regulation of synaptic assembly at neuromuscular junction GO:0008582 IMP     response to wounding GO:0009611 IMP     positive regulation of lamellipodium assembly GO:0010592 IMP     vesicle-mediated transport GO:0016192 IMP     ommatidial rotation GO:0016318 IGI     maintenance of cell polarity GO:0030011 IMP     cell projection organization GO:0030030 IMP     cell projection assembly GO:0030031 IMP     actin cytoskeleton organization GO:0030036 IMP     actin cytoskeleton organization GO:0030036 TAS     actin filament polymerization GO:0030041 IMP     regulation of actin filament polymerization GO:0030833 IDA     regulation of actin filament polymerization GO:0030833 IMP     cortical actin cytoskeleton organization GO:0030866 IMP     neuron projection development GO:0031175 IMP     encapsulation of foreign target GO:0035010 IMP     melanotic encapsulation of foreign target GO:0035011 IMP     hemocyte migration GO:0035099 IMP     branch fusion, open tracheal system GO:0035147 IMP     imaginal disc-derived wing hair outgrowth GO:0035318 IMP     wound healing GO:0042060 IMP     maintenance of protein location GO:0045185 IMP     establishment of neuroblast polarity GO:0045200 IMP     positive regulation of protein kinase activity GO:0045860 IMP     positive regulation of JNK cascade GO:0046330 IGI     dorsal closure, amnioserosa morphology change GO:0046664 IMP     dorsal appendage formation GO:0046843 IMP     regulation of neurotransmitter secretion GO:0046928 IMP     vascular endothelial growth factor receptor signaling pathway GO:0048010 IGI     oogenesis GO:0048477 TAS     axon extension GO:0048675 IGI     neuron projection morphogenesis GO:0048812 IMP     dendrite morphogenesis GO:0048813 IMP     regulation of axonogenesis GO:0050770 IGI     sensory perception of touch GO:0050975 IMP     positive regulation of filopodium assembly GO:0051491 IMP     exocyst localization GO:0051601 IMP     branching involved in open tracheal system development GO:0060446 IMP     protein localization to plasma membrane GO:0072659 IMP     positive regulation of wound healing GO:0090303 IMP     nephrocyte filtration GO:0097206 IMP Subcellular Localization     nucleus GO:0005634 IDA     cytoplasm GO:0005737 IDA     plasma membrane GO:0005886 HDA     cell cortex GO:0005938 IDA     rhabdomere GO:0016028 IMP     lamellipodium GO:0030027 IDA     axon GO:0030424 IDA     growth cone GO:0030426 IDA     apical part of cell GO:0045177 IDA