Gene description for Vps37b
Gene name vacuolar protein sorting 37B (yeast)
Gene symbol Vps37b
Other names/aliases 2300007F24Rik
AI415429
BC026744
Species Mus musculus
 Database cross references - Vps37b
ExoCarta ExoCarta_330192
Entrez Gene 330192
UniProt Q8R0J7  
 Vps37b identified in exosomes derived from the following tissue/cell type
Embryonic fibroblasts 18494037    
 Gene ontology annotations for Vps37b
Molecular Function
    calcium-dependent protein binding GO:0048306 ISO
Biological Process
    positive regulation of viral release from host cell GO:1902188 ISO
    transport GO:0006810 IEA
    protein transport GO:0015031 IEA
    positive regulation of viral budding via host ESCRT complex GO:1903774 ISO
Subcellular Localization
    midbody GO:0030496 ISO
    endosome membrane GO:0010008 ISO
    extracellular exosome GO:0070062 ISO
    cytoplasm GO:0005737 ISO
    plasma membrane GO:0005886 ISO
    endosome GO:0005768 ISO
    ESCRT I complex GO:0000813 ISO
    membrane GO:0016020 IEA
 Experiment description of studies that identified Vps37b in exosomes
1
Experiment ID 73
ISEV standards
✔
EM
EV Biophysical techniques
✔
HSP70|HSP90
EV Cytosolic markers
✘ EV Membrane markers
✘ EV Negative markers
✘ EV Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 18494037    
Organism Mus musculus
Experiment description Difference gel electrophoresis analysis of Ras-transformed fibroblast cell-derived exosomes.
Authors Ji H, Erfani N, Tauro BJ, Kapp EA, Zhu HJ, Moritz RL, Lim JW, Simpson RJ
Journal name ELEC
Publication year 2008
Sample Embryonic fibroblasts
Sample name NIH3T3
Isolation/purification methods Differential centrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry [LCQ DECA]
Western blotting
 Protein-protein interactions for Vps37b
  Protein Interactor ExoCarta ID Identification method PubMed Species
No interactions are found.
 Pathways in which Vps37b is involved
PathwayEvidenceSource
Endosomal Sorting Complex Required For Transport (ESCRT) IEA Reactome





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