Gene description for aru
Gene name arouser
Gene symbol aru
Other names/aliases CG4276
DmelCG4276
EPS8L3
Species Drosophila melanogaster
 Database cross references - aru
ExoCarta ExoCarta_33268
Entrez Gene 33268
 aru identified in exosomes derived from the following tissue/cell type
Drosophila S2 cells 23035643    
 Gene ontology annotations for aru
Molecular Function
    structural constituent of ribosome GO:0003735 IEA
Biological Process
    epidermal growth factor receptor signaling pathway GO:0007173 NAS
    olfactory behavior GO:0042048 IDA
    response to ethanol GO:0045471 IDA
    regulation of synapse structure or activity GO:0050803 IDA
    memory GO:0007613 IDA
    translation GO:0006412 IEA
Subcellular Localization
    ribosome GO:0005840 IEA
    synapse GO:0045202 IDA
 Experiment description of studies that identified aru in exosomes
1
Experiment ID 202
ISEV standards
IEM
EV Biophysical techniques
TSG10|RAB35
EV Cytosolic markers
FLOT2
EV Membrane markers
EV Negative markers
EV Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 23035643    
Organism Drosophila melanogaster
Experiment description Drosophila S2 cells secrete Wingless on exosome-like vesicles but the Wingless gradient forms independently of exosomes.
Authors Beckett K, Monier S, Palmer L, Alexandre C, Green H, Bonneil E, Raposo G, Thibault P, Borgne RL, Vincent JP.
Journal name Traffic
Publication year 2012
Sample Drosophila S2 cells
Sample name Normal-Drosophila S2 tub-Wg
Isolation/purification methods Filtration
Ultracentrifugation
Sucrose density gradient
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
 Protein-protein interactions for aru
  Protein Interactor ExoCarta ID Identification method PubMed Species
No interactions are found.
 Pathways in which aru is involved
No pathways found





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