Gene description for aru
Gene name arouser
Gene symbol aru
Other names/aliases CG4276
DmelCG4276
EPS8L3
Species Drosophila melanogaster
 Database cross references - aru
ExoCarta ExoCarta_33268
Vesiclepedia VP_33268
Entrez Gene 33268
 aru identified in sEVs derived from the following tissue/cell type
Drosophila S2 cells 23035643    
 Gene ontology annotations for aru
Biological Process
    memory GO:0007613 IDA
    olfactory behavior GO:0042048 IDA
    response to ethanol GO:0045471 IDA
    regulation of synapse structure or activity GO:0050803 IDA
Subcellular Localization
    synapse GO:0045202 IDA
 Experiment description of studies that identified aru in sEVs
1
Experiment ID 202
MISEV standards
IEM
Biophysical techniques
TSG10|RAB35|FLOT2
Enriched markers
Negative markers
Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 23035643    
Organism Drosophila melanogaster
Experiment description Drosophila S2 cells secrete Wingless on exosome-like vesicles but the Wingless gradient forms independently of exosomes.
Authors "Beckett K, Monier S, Palmer L, Alexandre C, Green H, Bonneil E, Raposo G, Thibault P, Borgne RL, Vincent JP."
Journal name Traffic
Publication year 2012
Sample Drosophila S2 cells
Sample name Normal-Drosophila S2 tub-Wg
Isolation/purification methods Filtration
Ultracentrifugation
Sucrose density gradient
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
 Protein-protein interactions for aru
  Protein Interactor ExoCarta ID Identification method PubMed Species
1 P32  
Two-hybrid Drosophila melanogaster
2 CG9394  
Two-hybrid Drosophila melanogaster
3 CG13510  
Two-hybrid Drosophila melanogaster
4 yps  
Two-hybrid Drosophila melanogaster
5 CG8159  
Two-hybrid Drosophila melanogaster
6 spi  
Two-hybrid Drosophila melanogaster
7 CG12861  
Two-hybrid Drosophila melanogaster
8 CG14551  
Two-hybrid Drosophila melanogaster
9 Sar1  
Two-hybrid Drosophila melanogaster
10 CG3213  
Two-hybrid Drosophila melanogaster
11 CG12985  
Two-hybrid Drosophila melanogaster
12 ssp2  
Two-hybrid Drosophila melanogaster
13 CG12316  
Two-hybrid Drosophila melanogaster
14 CG31121  
Two-hybrid Drosophila melanogaster
15 CG5346  
Two-hybrid Drosophila melanogaster
16 CG6695  
Two-hybrid Drosophila melanogaster
17 Tak1  
Affinity Capture-MS Drosophila melanogaster
18 CG3605  
Two-hybrid Drosophila melanogaster
19 key  
Affinity Capture-MS Drosophila melanogaster
20 CG9426  
Two-hybrid Drosophila melanogaster
21 CG44837  
Two-hybrid Drosophila melanogaster
22 nopo  
Two-hybrid Drosophila melanogaster
23 CG7800  
Two-hybrid Drosophila melanogaster
24 CG15646  
Two-hybrid Drosophila melanogaster
25 RpL10Ab  
Two-hybrid Drosophila melanogaster
26 CG6040  
Two-hybrid Drosophila melanogaster
27 imd  
Affinity Capture-MS Drosophila melanogaster
28 CG15423  
Two-hybrid Drosophila melanogaster
29 CG3081  
Two-hybrid Drosophila melanogaster
30 Iap2  
Affinity Capture-MS Drosophila melanogaster
31 PGRP-LE  
Affinity Capture-MS Drosophila melanogaster
32 MEP-1  
Two-hybrid Drosophila melanogaster
33 CG17666  
Two-hybrid Drosophila melanogaster
34 CG18259  
Two-hybrid Drosophila melanogaster
35 skpB  
Two-hybrid Drosophila melanogaster
36 CG15482  
Two-hybrid Drosophila melanogaster
37 CG2889  
Two-hybrid Drosophila melanogaster
38 Tango2  
Two-hybrid Drosophila melanogaster
39 RpL4  
Two-hybrid Drosophila melanogaster
40 CG11906  
Two-hybrid Drosophila melanogaster
41 CG5522  
Two-hybrid Drosophila melanogaster
42 CG43691  
Two-hybrid Drosophila melanogaster
43 Rgk2  
Two-hybrid Drosophila melanogaster
44 Rel  
Affinity Capture-MS Drosophila melanogaster
45 odd  
Two-hybrid Drosophila melanogaster
46 ird5  
Affinity Capture-MS Drosophila melanogaster
47 CG4229  
Two-hybrid Drosophila melanogaster
48 CTPsyn  
Proximity Label-MS Drosophila melanogaster
49 CG5089  
Two-hybrid Drosophila melanogaster
50 Taf12  
Two-hybrid Drosophila melanogaster
51 CG13737  
Two-hybrid Drosophila melanogaster
52 IM3  
Two-hybrid Drosophila melanogaster
53 slik  
Affinity Capture-MS Drosophila melanogaster
54 Pnn  
Two-hybrid Drosophila melanogaster
55 Rpt4  
Two-hybrid Drosophila melanogaster
56 cactin  
Two-hybrid Drosophila melanogaster
57 Tab2  
Affinity Capture-MS Drosophila melanogaster
58 sinah  
Two-hybrid Drosophila melanogaster
59 CG10435  
Two-hybrid Drosophila melanogaster
60 ND75  
Two-hybrid Drosophila melanogaster
61 CG9914  
Two-hybrid Drosophila melanogaster
62 Myb  
Two-hybrid Drosophila melanogaster
View the network image/svg+xml
 Pathways in which aru is involved
No pathways found





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