Gene description for Trip1
Gene name CG8882 gene product from transcript CG8882-RA
Gene symbol Trip1
Other names/aliases CG8882
DmTRIP
DmelCG8882
eIF-3beta
eIF3-S2
Species Drosophila melanogaster
 Database cross references - Trip1
ExoCarta ExoCarta_33710
Vesiclepedia VP_33710
Entrez Gene 33710
UniProt O02195  
 Trip1 identified in exosomes derived from the following tissue/cell type
Drosophila S2 cells 23035643    
 Gene ontology annotations for Trip1
Molecular Function
    translation initiation factor activity GO:0003743 ISS
Biological Process
    translational initiation GO:0006413 ISS
Subcellular Localization
    eukaryotic translation initiation factor 3 complex GO:0005852 ISS
 Experiment description of studies that identified Trip1 in exosomes
1
Experiment ID 202
MISEV standards
✔
IEM
Biophysical techniques
✔
TSG10|RAB35|FLOT2
Enriched markers
✘ Negative markers
✘ Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 23035643    
Organism Drosophila melanogaster
Experiment description Drosophila S2 cells secrete Wingless on exosome-like vesicles but the Wingless gradient forms independently of exosomes.
Authors "Beckett K, Monier S, Palmer L, Alexandre C, Green H, Bonneil E, Raposo G, Thibault P, Borgne RL, Vincent JP."
Journal name Traffic
Publication year 2012
Sample Drosophila S2 cells
Sample name Normal-Drosophila S2 tub-Wg
Isolation/purification methods Filtration
Ultracentrifugation
Sucrose density gradient
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
 Protein-protein interactions for Trip1
  Protein Interactor ExoCarta ID Identification method PubMed Species
1 CTPsyn  
Proximity Label-MS Drosophila melanogaster
2 Sin3A  
Two-hybrid Drosophila melanogaster
3 mts  
Two-hybrid Drosophila melanogaster
4 E2f2  
Two-hybrid Drosophila melanogaster
5 BM-40-SPARC  
Two-hybrid Drosophila melanogaster
6 CG4998  
Two-hybrid Drosophila melanogaster
7 imd  
Two-hybrid Drosophila melanogaster
8 Dfd  
Two-hybrid Drosophila melanogaster
9 Su(var)3-9  
Two-hybrid Drosophila melanogaster
10 CG14671  
Two-hybrid Drosophila melanogaster
11 Ibf2  
Two-hybrid Drosophila melanogaster
View the network image/svg+xml



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