ExoCarta: Gene summary

Credits | Contact

Gene description for RPS15A
Gene name	ribosomal protein S15a
Gene symbol	RPS15A
Other names/aliases	-
Species	Bos taurus
Database cross references - RPS15A
ExoCarta	ExoCarta_337888
Entrez Gene	337888
UniProt	Q76I82
RPS15A identified in exosomes derived from the following tissue/cell type
Milk	23459212

Gene ontology annotations for RPS15A

Molecular Function
	structural constituent of ribosome	GO:0003735	IBA
	poly(A) RNA binding	GO:0044822	IEA
Biological Process
	response to virus	GO:0009615	IEA
	translation	GO:0006412	IEA
	positive regulation of cell proliferation	GO:0008284	IEA
	positive regulation of cell cycle	GO:0045787	IEA
Subcellular Localization
	cytosolic small ribosomal subunit	GO:0022627	IEA
	extracellular exosome	GO:0070062	IEA
	membrane	GO:0016020	IEA

Experiment description of studies that identified RPS15A in exosomes

Experiment ID

213

ISEV standards
✘	EV Biophysical techniques
✘	EV Cytosolic markers
✘	EV Membrane markers
✘	EV Negative markers
✘	EV Particle analysis

Identified molecule

protein

Identification method

Mass spectrometry

PubMed ID

23459212

Organism

Bos taurus

Experiment description

Bovine milk proteome: Quantitative changes in normal milk exosomes, milk fat globule membranes and whey proteomes resulting from Staphylococcus aureus mastitis.

Authors

Reinhardt TA, Sacco RE, Nonnecke BJ, Lippolis JD.

Journal name

J Proteomics

Publication year

2013

Sample

Milk

Sample name

Staphylococcus aureus-infected-Milk

Isolation/purification methods

Differential centrifugation
Ultracentrifugation
Filtration
Sucrose density gradient
FACS

Flotation density

Molecules identified in the study

Protein

Methods used in the study

Mass spectrometry

Protein-protein interactions for RPS15A

	Protein Interactor	ExoCarta ID	Identification method	PubMed	Species
No interactions are found.

Pathways in which RPS15A is involved

Pathway	Evidence	Source
Eukaryotic Translation Termination	IEA	Reactome
Formation of a pool of free 40S subunits	IEA	Reactome
Formation of the ternary complex, and subsequently, the 43S complex	IEA	Reactome
GTP hydrolysis and joining of the 60S ribosomal subunit	IEA	Reactome
L13a-mediated translational silencing of Ceruloplasmin expression	IEA	Reactome
Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)	IEA	Reactome
Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)	IEA	Reactome
Peptide chain elongation	IEA	Reactome
Ribosomal scanning and start codon recognition	IEA	Reactome
SRP-dependent cotranslational protein targeting to membrane	IEA	Reactome
Translation initiation complex formation	IEA	Reactome

Perform bioinformatics analysis of your extracellular vesicle data set using FunRich, a open access standalone tool. NEW UPDATED VERSION OF FunRich available for download (12/09/2016) from here