Gene description for RHOA
Gene name ras homolog family member A
Gene symbol RHOA
Other names/aliases ARHA
Species Bos taurus
 Database cross references - RHOA
ExoCarta ExoCarta_338049
Entrez Gene 338049
UniProt P61585  
 RHOA identified in exosomes derived from the following tissue/cell type
Milk 23459212    
 Gene ontology annotations for RHOA
Molecular Function
    GTP binding GO:0005525 IEA
    myosin binding GO:0017022 IEA
Biological Process
    negative chemotaxis GO:0050919 IEA
    positive regulation of I-kappaB kinase/NF-kappaB signaling GO:0043123 ISS
    mitotic spindle assembly GO:0090307 IEA
    skeletal muscle satellite cell migration GO:1902766 ISS
    apolipoprotein A-I-mediated signaling pathway GO:0038027 IEA
    apical junction assembly GO:0043297 ISS
    positive regulation of neuron differentiation GO:0045666 IEA
    small GTPase mediated signal transduction GO:0007264 IEA
    regulation of cell migration GO:0030334 ISS
    positive regulation of stress fiber assembly GO:0051496 IEA
    substantia nigra development GO:0021762 IEA
    positive regulation of cytokinesis GO:0032467 ISS
    wound healing, spreading of cells GO:0044319 ISS
    cleavage furrow formation GO:0036089 ISS
Subcellular Localization
    cytoskeleton GO:0005856 IEA
    cleavage furrow GO:0032154 IEA
    lamellipodium GO:0030027 ISS
    plasma membrane GO:0005886 IEA
    apical junction complex GO:0043296 ISS
    midbody GO:0030496 IEA
    focal adhesion GO:0005925 IEA
    cell cortex GO:0005938 ISS
    extracellular exosome GO:0070062 IEA
 Experiment description of studies that identified RHOA in exosomes
1
Experiment ID 213
ISEV standards
EV Biophysical techniques
EV Cytosolic markers
EV Membrane markers
EV Negative markers
EV Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 23459212    
Organism Bos taurus
Experiment description Bovine milk proteome: Quantitative changes in normal milk exosomes, milk fat globule membranes and whey proteomes resulting from Staphylococcus aureus mastitis.
Authors Reinhardt TA, Sacco RE, Nonnecke BJ, Lippolis JD.
Journal name J Proteomics
Publication year 2013
Sample Milk
Sample name Staphylococcus aureus-infected-Milk
Isolation/purification methods Differential centrifugation
Ultracentrifugation
Filtration
Sucrose density gradient
FACS
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
 Protein-protein interactions for RHOA
  Protein Interactor ExoCarta ID Identification method PubMed Species
No interactions are found.



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