Gene description for ATP6V1B2
Gene name ATPase, H+ transporting, lysosomal 56/58kDa, V1 subunit B2
Gene symbol ATP6V1B2
Other names/aliases -
Species Bos taurus
 Database cross references - ATP6V1B2
ExoCarta ExoCarta_338082
Entrez Gene 338082
UniProt P31408  
 ATP6V1B2 identified in exosomes derived from the following tissue/cell type
Milk 23459212    
 Gene ontology annotations for ATP6V1B2
Molecular Function
    hydrolase activity, acting on acid anhydrides, catalyzing transmembrane movement of substances GO:0016820 IEA
    ATP binding GO:0005524 IEA
Biological Process
    ATP metabolic process GO:0046034 IEA
    ATP hydrolysis coupled proton transport GO:0015991 IEA
Subcellular Localization
    ruffle GO:0001726 IEA
    extracellular exosome GO:0070062 IEA
    proton-transporting V-type ATPase, V1 domain GO:0033180 IEA
    endomembrane system GO:0012505 IEA
    microvillus GO:0005902 IEA
    cytosol GO:0005829 ISS
    plasma membrane GO:0005886 ISS
    lysosomal membrane GO:0005765 IEA
    melanosome GO:0042470 IEA
 Experiment description of studies that identified ATP6V1B2 in exosomes
1
Experiment ID 213
ISEV standards
EV Biophysical techniques
EV Cytosolic markers
EV Membrane markers
EV Negative markers
EV Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 23459212    
Organism Bos taurus
Experiment description Bovine milk proteome: Quantitative changes in normal milk exosomes, milk fat globule membranes and whey proteomes resulting from Staphylococcus aureus mastitis.
Authors Reinhardt TA, Sacco RE, Nonnecke BJ, Lippolis JD.
Journal name J Proteomics
Publication year 2013
Sample Milk
Sample name Staphylococcus aureus-infected-Milk
Isolation/purification methods Differential centrifugation
Ultracentrifugation
Filtration
Sucrose density gradient
FACS
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
 Protein-protein interactions for ATP6V1B2
  Protein Interactor ExoCarta ID Identification method PubMed Species
No interactions are found.
 Pathways in which ATP6V1B2 is involved
PathwayEvidenceSource
Insulin receptor recycling IEA Reactome
Ion channel transport IEA Reactome
Transferrin endocytosis and recycling IEA Reactome





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