Gene description for COPE
Gene name coatomer protein complex, subunit epsilon
Gene symbol COPE
Other names/aliases -
Species Bos taurus
 Database cross references - COPE
ExoCarta ExoCarta_338085
Entrez Gene 338085
UniProt Q28104  
 COPE identified in exosomes derived from the following tissue/cell type
Milk 23459212    
 Gene ontology annotations for COPE
Molecular Function
    structural molecule activity GO:0005198 IEA
    protein binding GO:0005515 IPI
Biological Process
    retrograde vesicle-mediated transport, Golgi to ER GO:0006890 TAS
    intra-Golgi vesicle-mediated transport GO:0006891 IDA
    ER to Golgi vesicle-mediated transport GO:0006888 IBA
    protein transport GO:0015031 IEA
Subcellular Localization
    nucleoplasm GO:0005654 IEA
    COPI vesicle coat GO:0030126 IDA
 Experiment description of studies that identified COPE in exosomes
Experiment ID 213
ISEV standards
EV Biophysical techniques
EV Cytosolic markers
EV Membrane markers
EV Negative markers
EV Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 23459212    
Organism Bos taurus
Experiment description Bovine milk proteome: Quantitative changes in normal milk exosomes, milk fat globule membranes and whey proteomes resulting from Staphylococcus aureus mastitis.
Authors Reinhardt TA, Sacco RE, Nonnecke BJ, Lippolis JD.
Journal name J Proteomics
Publication year 2013
Sample Milk
Sample name Staphylococcus aureus-infected-Milk
Isolation/purification methods Differential centrifugation
Sucrose density gradient
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
 Protein-protein interactions for COPE
  Protein Interactor ExoCarta ID Identification method PubMed Species
No interactions are found.
 Pathways in which COPE is involved
COPI Mediated Transport IEA Reactome

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