Gene description for Ent2
Gene name Equilibrative nucleoside transporter 2
Gene symbol Ent2
Other names/aliases BEST:LD04971
Species Drosophila melanogaster
 Database cross references - Ent2
ExoCarta ExoCarta_33921
Entrez Gene 33921
 Ent2 identified in exosomes derived from the following tissue/cell type
Drosophila S2 cells 23035643    
 Gene ontology annotations for Ent2
Molecular Function
    nucleoside transmembrane transporter activity GO:0005337 ISS
Biological Process
    nucleoside transport GO:0015858 ISS
    negative regulation of calcium ion import GO:0090281 IMP
    associative learning GO:0008306 IMP
    synaptic transmission GO:0007268 IMP
Subcellular Localization
    integral component of membrane GO:0016021 ISM
    plasma membrane GO:0005886 IDA
 Experiment description of studies that identified Ent2 in exosomes
Experiment ID 202
ISEV standards
EV Biophysical techniques
EV Cytosolic markers
EV Membrane markers
EV Negative markers
EV Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 23035643    
Organism Drosophila melanogaster
Experiment description Drosophila S2 cells secrete Wingless on exosome-like vesicles but the Wingless gradient forms independently of exosomes.
Authors Beckett K, Monier S, Palmer L, Alexandre C, Green H, Bonneil E, Raposo G, Thibault P, Borgne RL, Vincent JP.
Journal name Traffic
Publication year 2012
Sample Drosophila S2 cells
Sample name Normal-Drosophila S2 tub-Wg
Isolation/purification methods Filtration
Sucrose density gradient
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
 Protein-protein interactions for Ent2
  Protein Interactor ExoCarta ID Identification method PubMed Species
No interactions are found.
 Pathways in which Ent2 is involved
No pathways found

Perform bioinformatics analysis of your extracellular vesicle data set using FunRich, a open access standalone tool. NEW UPDATED VERSION OF FunRich available for download (12/09/2016) from here