Gene description for Rab30
Gene name CG9100 gene product from transcript CG9100-RB
Gene symbol Rab30
Other names/aliases AAF52477
CG9100
DmRab30
DmelCG9100
Q9VM50
rab30
Species Drosophila melanogaster
 Database cross references - Rab30
ExoCarta ExoCarta_33988
Entrez Gene 33988
 Rab30 identified in exosomes derived from the following tissue/cell type
Drosophila S2 cells 23035643    
 Gene ontology annotations for Rab30
Molecular Function
    GTP binding GO:0005525 IEA
    protein binding GO:0005515 IPI
    GTPase activity GO:0003924 ISS
Biological Process
    vesicle-mediated transport GO:0016192 ISS
    protein transport GO:0015031 IEA
    imaginal disc fusion, thorax closure GO:0046529 IMP
    germ-band shortening GO:0007390 IMP
    head involution GO:0008258 IMP
    dorsal closure GO:0007391 IMP
    Rab protein signal transduction GO:0032482 ISS
Subcellular Localization
    vesicle GO:0031982 ISS
    trans-Golgi network GO:0005802 IDA
    synapse GO:0045202 IDA
    Golgi apparatus GO:0005794 IDA
    endosome GO:0005768 IDA
    cytoplasmic vesicle GO:0031410 IDA
 Experiment description of studies that identified Rab30 in exosomes
1
Experiment ID 202
ISEV standards
IEM
EV Biophysical techniques
TSG10|RAB35
EV Cytosolic markers
FLOT2
EV Membrane markers
EV Negative markers
EV Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 23035643    
Organism Drosophila melanogaster
Experiment description Drosophila S2 cells secrete Wingless on exosome-like vesicles but the Wingless gradient forms independently of exosomes.
Authors Beckett K, Monier S, Palmer L, Alexandre C, Green H, Bonneil E, Raposo G, Thibault P, Borgne RL, Vincent JP.
Journal name Traffic
Publication year 2012
Sample Drosophila S2 cells
Sample name Normal-Drosophila S2 tub-Wg
Isolation/purification methods Filtration
Ultracentrifugation
Sucrose density gradient
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
 Protein-protein interactions for Rab30
  Protein Interactor ExoCarta ID Identification method PubMed Species
No interactions are found.
 Pathways in which Rab30 is involved
No pathways found





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