Gene description for SLC6A19
Gene name solute carrier family 6 (neutral amino acid transporter), member 19
Gene symbol SLC6A19
Other names/aliases B0AT1
HND
Species Homo sapiens
 Database cross references - SLC6A19
ExoCarta ExoCarta_340024
Vesiclepedia VP_340024
Entrez Gene 340024
HGNC 27960
MIM 608893
UniProt Q695T7  
 SLC6A19 identified in sEVs derived from the following tissue/cell type
Urine 19056867    
Urine 22418980    
Urine 22418980    
 Gene ontology annotations for SLC6A19
Molecular Function
    protein binding GO:0005515 IPI
    amino acid transmembrane transporter activity GO:0015171 TAS
    neutral L-amino acid transmembrane transporter activity GO:0015175 IBA
    neutral L-amino acid transmembrane transporter activity GO:0015175 IDA
    symporter activity GO:0015293 IEA
Biological Process
    amino acid transmembrane transport GO:0003333 IEA
    amino acid transport GO:0006865 TAS
    response to nutrient GO:0007584 IEA
    neutral amino acid transport GO:0015804 IBA
    viral life cycle GO:0019058 NAS
    sodium ion transmembrane transport GO:0035725 IBA
Subcellular Localization
    plasma membrane GO:0005886 IBA
    plasma membrane GO:0005886 TAS
    apical plasma membrane GO:0016324 IBA
    apical plasma membrane GO:0016324 IDA
    brush border membrane GO:0031526 IBA
    brush border membrane GO:0031526 IDA
    extracellular exosome GO:0070062 HDA
 Experiment description of studies that identified SLC6A19 in sEVs
1
Experiment ID 63
MISEV standards
✘ Biophysical techniques
✔
AQP2
Enriched markers
✘ Negative markers
✘ Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 19056867    
Organism Homo sapiens
Experiment description Large-scale proteomics and phosphoproteomics of urinary exosomes.
Authors "Gonzales PA, Pisitkun T, Hoffert JD, Tchapyjnikov D, Star RA, Kleta R, Wang NS, Knepper MA"
Journal name JASN
Publication year 2009
Sample Urine
Sample name Urine - Normal
Isolation/purification methods Differential centrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry [LTQ]
Western blotting
2
Experiment ID 196
MISEV standards
✔
EM
Biophysical techniques
✔
Alix|TSG101|HSP70|CD9
Enriched markers
✘ Negative markers
✘ Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 22418980    
Organism Homo sapiens
Experiment description A multiplex quantitative proteomics strategy for protein biomarker studies in urinary exosomes.
Authors "Raj DA, Fiume I, Capasso G, Pocsfalvi G."
Journal name Kidney Int
Publication year 2012
Sample Urine
Sample name Urine - Normal high density
Isolation/purification methods Differential centrifugation
Sucrose cushion
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
3
Experiment ID 197
MISEV standards
✔
EM
Biophysical techniques
✔
Alix|TSG101|HSP70|CD9
Enriched markers
✘ Negative markers
✘ Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 22418980    
Organism Homo sapiens
Experiment description A multiplex quantitative proteomics strategy for protein biomarker studies in urinary exosomes.
Authors "Raj DA, Fiume I, Capasso G, Pocsfalvi G."
Journal name Kidney Int
Publication year 2012
Sample Urine
Sample name Urine - Normal low density
Isolation/purification methods Differential centrifugation
Sucrose cushion
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
 Protein-protein interactions for SLC6A19
  Protein Interactor ExoCarta ID Identification method PubMed Species
No interactions are found.



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