Gene description for wg
Gene name	wingless
Gene symbol	wg
Other names/aliases	Br CG4889 DWint-1 DWnt-1 Dint-1 Dm Wg Dm-1 DmelCG4889 Gla I Sp WG WNT Wg Wnt Wnt-1 Wnt/Wg Wnt1 dWnt fg int-1 l(2)02657 l(2)rO727 l(2)wg spd wgl wnt wnt1
Species	Drosophila melanogaster
Database cross references - wg
ExoCarta	ExoCarta_34009
Vesiclepedia	VP_34009
Entrez Gene	34009
UniProt	P09615
wg identified in sEVs derived from the following tissue/cell type
Drosophila S2 cells	23035643

Gene ontology annotations for wg

Molecular Function     frizzled binding GO:0005109 IDA     frizzled binding GO:0005109 IPI     protein binding GO:0005515 IPI     glycosaminoglycan binding GO:0005539 IDA     morphogen activity GO:0016015 IDA     morphogen activity GO:0016015 IMP     heparan sulfate proteoglycan binding GO:0043395 IPI     receptor ligand activity GO:0048018 IDA     receptor ligand activity GO:0048018 IGI     extracellular matrix binding GO:0050840 IDA Biological Process     compound eye morphogenesis GO:0001745 IMP     segment polarity determination GO:0007367 IMP     dorsal closure GO:0007391 IMP     ectoderm development GO:0007398 IMP     ventral midline development GO:0007418 IMP     hindgut morphogenesis GO:0007442 IMP     imaginal disc development GO:0007444 IMP     anterior/posterior pattern specification, imaginal disc GO:0007448 IMP     dorsal/ventral pattern formation, imaginal disc GO:0007450 IMP     imaginal disc-derived wing morphogenesis GO:0007476 IMP     histoblast morphogenesis GO:0007488 IMP     mesoderm development GO:0007498 IMP     heart development GO:0007507 IMP     larval visceral muscle development GO:0007523 IMP     long-term memory GO:0007616 IMP     positive regulation of cell population proliferation GO:0008284 IGI     positive regulation of cell population proliferation GO:0008284 IMP     epidermis development GO:0008544 IMP     imaginal disc-derived wing margin morphogenesis GO:0008587 IGI     imaginal disc-derived wing margin morphogenesis GO:0008587 IMP     negative regulation of cell fate specification GO:0009996 IMP     cardioblast differentiation GO:0010002 IMP     neuroblast development GO:0014019 IMP     follicle cell of egg chamber development GO:0030707 IMP     negative regulation of DNA endoreduplication GO:0032876 IMP     branch fusion, open tracheal system GO:0035147 IMP     epithelial cell type specification, open tracheal system GO:0035153 IMP     larval lymph gland hemopoiesis GO:0035167 IMP     lymph gland crystal cell differentiation GO:0035170 IMP     labial disc development GO:0035217 IMP     wing disc development GO:0035220 IGI     genital disc anterior/posterior pattern formation GO:0035224 IEP     determination of genital disc primordium GO:0035225 IMP     genital disc sexually dimorphic development GO:0035263 IMP     spiracle morphogenesis, open tracheal system GO:0035277 IMP     chitin-based larval cuticle pattern formation GO:0035293 IMP     wing cell fate specification GO:0035311 IMP     tissue regeneration GO:0042246 IMP     positive regulation of crystal cell differentiation GO:0042691 IMP     positive regulation of programmed cell death GO:0043068 IMP     positive regulation of imaginal disc growth GO:0045572 IMP     negative regulation of hemocyte differentiation GO:0045611 IMP     positive regulation of compound eye retinal cell programmed cell death GO:0046672 IMP     regulation of compound eye pigmentation GO:0048076 IMP     mesoderm morphogenesis GO:0048332 IMP     lymph gland development GO:0048542 IMP     digestive tract morphogenesis GO:0048546 IMP     proboscis development GO:0048728 IMP     branching morphogenesis of an epithelial tube GO:0048754 IMP     synapse organization GO:0050808 IMP     synaptic assembly at neuromuscular junction GO:0051124 IMP     canonical Wnt signaling pathway GO:0060070 IDA     canonical Wnt signaling pathway GO:0060070 IGI     canonical Wnt signaling pathway GO:0060070 IMP     heart formation GO:0060914 IMP     pericardial nephrocyte differentiation GO:0061320 IMP     posterior Malpighian tubule development GO:0061328 IMP     epithelial cell proliferation involved in Malpighian tubule morphogenesis GO:0061331 IMP     Malpighian tubule bud morphogenesis GO:0061332 IMP     Malpighian tubule tip cell differentiation GO:0061382 IMP     regulation of stem cell proliferation GO:0072091 IMP     cell elongation involved in imaginal disc-derived wing morphogenesis GO:0090254 IDA     positive regulation of stem cell proliferation GO:2000648 IMP Subcellular Localization     extracellular region GO:0005576 IDA     extracellular space GO:0005615 IDA     early endosome GO:0005769 IDA     late endosome GO:0005770 IDA     multivesicular body GO:0005771 IDA     endoplasmic reticulum GO:0005783 IDA     plasma membrane GO:0005886 IDA     cell surface GO:0009986 IDA     terminal bouton GO:0043195 IDA     membrane raft GO:0045121 IDA