Gene description for wg
Gene name	wingless
Gene symbol	wg
Other names/aliases	Br CG4889 DWint-1 DWnt-1 Dint-1 Dm Wg Dm-1 DmelCG4889 Gla I Sp WG WNT Wg Wnt Wnt-1 Wnt/Wg Wnt1 dWnt fg int-1 l(2)02657 l(2)rO727 l(2)wg spd wgl wnt wnt1
Species	Drosophila melanogaster
Database cross references - wg
ExoCarta	ExoCarta_34009
Entrez Gene	34009
UniProt	P09615
wg identified in exosomes derived from the following tissue/cell type
Drosophila S2 cells	23035643

Gene ontology annotations for wg

Molecular Function     frizzled-2 binding GO:0005110 IPI     receptor binding GO:0005102 NAS     glycosaminoglycan binding GO:0005539 IDA     protein binding GO:0005515 IPI     morphogen activity GO:0016015 TAS     heparan sulfate proteoglycan binding GO:0043395 IPI     extracellular matrix binding GO:0050840 IDA     frizzled binding GO:0005109 IPI     Notch binding GO:0005112 TAS Biological Process     Malpighian tubule bud morphogenesis GO:0061332 IMP     mesoderm development GO:0007498 IMP     positive regulation of compound eye retinal cell programmed cell death GO:0046672 IMP     spiracle morphogenesis, open tracheal system GO:0035277 IMP     leg disc proximal/distal pattern formation GO:0007479 TAS     canonical Wnt signaling pathway GO:0060070 IGI     regulation of mitotic cell cycle GO:0007346 TAS     Wnt signaling pathway, calcium modulating pathway GO:0007223 IGI     sensory organ development GO:0007423 TAS     wing cell fate specification GO:0035311 IMP     proboscis development GO:0048728 IMP     Wnt signaling pathway GO:0016055 NAS     epidermis development GO:0008544 IMP     regulation of imaginal disc-derived wing size GO:0044719 IMP     dorsal/ventral pattern formation, imaginal disc GO:0007450 TAS     ectoderm development GO:0007398 IMP     negative regulation of hemocyte differentiation GO:0045611 IMP     branch fusion, open tracheal system GO:0035147 IMP     filopodium assembly GO:0046847 IMP     cardioblast differentiation GO:0010002 IMP     genital disc development GO:0035215 TAS     ommatidial rotation GO:0016318 TAS     trunk segmentation GO:0035290 TAS     genital disc sexually dimorphic development GO:0035263 IMP     axis specification GO:0009798 IBA     midbrain-hindbrain boundary development GO:0030917 IBA     negative regulation of phosphorylation GO:0042326 NAS     negative regulation of apoptotic process GO:0043066 TAS     regulation of stem cell proliferation GO:0072091 IMP     synaptic growth at neuromuscular junction GO:0051124 IMP     hindgut morphogenesis GO:0007442 IMP     synapse organization GO:0050808 IMP     positive regulation of crystal cell differentiation GO:0042691 IMP     instar larval development GO:0002168 TAS     ventral midline development GO:0007418 IMP     segment polarity determination GO:0007367 TAS     negative regulation of transcription from RNA polymerase II promoter GO:0000122 IBA     positive regulation of transcription from RNA polymerase II promoter GO:0045944 IBA     lymph gland development GO:0048542 IMP     genital disc anterior/posterior pattern formation GO:0035224 IEP     epithelial cell proliferation involved in Malpighian tubule morphogenesis GO:0061331 IMP     positive regulation of cell proliferation GO:0008284 IMP     Malpighian tubule tip cell differentiation GO:0061382 IMP     larval lymph gland hemopoiesis GO:0035167 IMP     imaginal disc growth GO:0007446 TAS     cuticle pattern formation GO:0035017 IMP     long-term memory GO:0007616 IMP     positive regulation of stem cell proliferation GO:2000648 IMP     posterior head segmentation GO:0035289 TAS     negative regulation of DNA endoreduplication GO:0032876 IMP     negative regulation of fat cell differentiation GO:0045599 IBA     negative regulation of cell fate specification GO:0009996 IMP     imaginal disc-derived wing morphogenesis GO:0007476 IMP     actin filament bundle assembly GO:0051017 IMP     imaginal disc development GO:0007444 IMP     dorsal closure GO:0007391 IMP     dorsal closure, elongation of leading edge cells GO:0007394 IMP     mesoderm morphogenesis GO:0048332 IMP     epithelial cell type specification, open tracheal system GO:0035153 IMP     negative regulation of transcription, DNA-templated GO:0045892 IMP     compound eye morphogenesis GO:0001745 IMP     neuroblast development GO:0014019 IMP     regulation of cell proliferation GO:0042127 NAS     wing disc dorsal/ventral pattern formation GO:0048190 TAS     branching morphogenesis of an epithelial tube GO:0048754 IMP     wing disc development GO:0035220 IGI     regulation of transcription, DNA-templated GO:0006355 IMP     anterior head segmentation GO:0035288 TAS     heart development GO:0007507 IMP     lamellipodium assembly GO:0030032 IMP     heart formation GO:0060914 IMP     posterior Malpighian tubule development GO:0061328 IMP     pericardial nephrocyte differentiation GO:0061320 IMP     negative regulation of heart induction by canonical Wnt signaling pathway GO:0003136 IMP     lymph gland crystal cell differentiation GO:0035170 IMP     anterior/posterior pattern specification, imaginal disc GO:0007448 IMP     larval visceral muscle development GO:0007523 IMP     ovarian follicle cell development GO:0030707 IMP     somatic stem cell maintenance GO:0035019 IBA     determination of genital disc primordium GO:0035225 IMP     anterior/posterior axis specification, embryo GO:0008595 TAS     ventral cord development GO:0007419 TAS     compound eye development GO:0048749 TAS     regulation of compound eye pigmentation GO:0048076 IMP     labial disc development GO:0035217 IMP     imaginal disc pattern formation GO:0007447 TAS Subcellular Localization     multivesicular body GO:0005771 IDA     extracellular region GO:0005576 TAS     terminal bouton GO:0043195 IDA     plasma membrane GO:0005886 IDA     late endosome GO:0005770 IDA     membrane raft GO:0045121 IDA     cytoplasmic membrane-bounded vesicle GO:0016023 NAS     extracellular space GO:0005615 IDA     early endosome GO:0005769 IDA     endocytic vesicle GO:0030139 IDA     endoplasmic reticulum GO:0005783 IDA     cell surface GO:0009986 IDA