Gene description for OR2T8
Gene name olfactory receptor, family 2, subfamily T, member 8
Gene symbol OR2T8
Other names/aliases OR2T8P
Species Homo sapiens
 Database cross references - OR2T8
ExoCarta ExoCarta_343172
Vesiclepedia VP_343172
Entrez Gene 343172
HGNC 15020
UniProt A6NH00  
 OR2T8 identified in exosomes derived from the following tissue/cell type
Hepatocellular carcinoma cells 26054723    
 Gene ontology annotations for OR2T8
Molecular Function
    olfactory receptor activity GO:0004984 IBA
    G-protein coupled receptor activity GO:0004930 IEA
Biological Process
    sensory perception of smell GO:0007608 IBA
    detection of chemical stimulus involved in sensory perception of smell GO:0050911 IEA
    G-protein coupled receptor signaling pathway GO:0007186 IBA
Subcellular Localization
    integral component of membrane GO:0016021 IBA
    plasma membrane GO:0005886 TAS
 Experiment description of studies that identified OR2T8 in exosomes
1
Experiment ID 235
MISEV standards
✔
EM
EV Biophysical techniques
✔
TSG101|Alix|HSC70|GAPDH
EV Enriched markers
✔
HSP90B1
EV Negative markers
✔
qNano
EV Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 26054723    
Organism Homo sapiens
Experiment description Hepatocellular carcinoma-derived exosomes promote motility of immortalized hepatocyte through transfer of oncogenic proteins and RNAs
Authors He M, Qin H, Poon TC, Sze SC, Ding X, Co NN, Ngai SM, Chan TF, Wong N
Journal name Carcinogenesis
Publication year 2015
Sample Hepatocellular carcinoma cells
Sample name HKCI-8
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Sucrose density gradient
Flotation density 1.13-1.19 g/mL
Molecules identified in the study Protein
RNA
Methods used in the study Western blotting
Mass spectrometry
RT-PCR
RNA Sequencing
 Protein-protein interactions for OR2T8
  Protein Interactor ExoCarta ID Identification method PubMed Species
No interactions are found.
 Pathways in which OR2T8 is involved
PathwayEvidenceSource
Olfactory Signaling Pathway TAS Reactome





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