Gene description for Stam
Gene name Signal transducing adaptor molecule
Gene symbol Stam
Other names/aliases CG6521
DmelCG6521
Dstam
STAM
Stam1
dstam
stam
Species Drosophila melanogaster
 Database cross references - Stam
ExoCarta ExoCarta_34505
Vesiclepedia VP_34505
Entrez Gene 34505
 Stam identified in sEVs derived from the following tissue/cell type
Drosophila S2 cells 23035643    
 Gene ontology annotations for Stam
Biological Process
    epithelial cell migration, open tracheal system GO:0007427 IMP
    endosomal transport GO:0016197 IMP
    neuron remodeling GO:0016322 IGI
    wound healing GO:0042060 HMP
    regulation of cell cycle GO:0051726 IGI
    regulation of epithelial cell migration, open tracheal system GO:2000274 IMP
 Experiment description of studies that identified Stam in sEVs
1
Experiment ID 202
MISEV standards
IEM
Biophysical techniques
TSG10|RAB35|FLOT2
Enriched markers
Negative markers
Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 23035643    
Organism Drosophila melanogaster
Experiment description Drosophila S2 cells secrete Wingless on exosome-like vesicles but the Wingless gradient forms independently of exosomes.
Authors "Beckett K, Monier S, Palmer L, Alexandre C, Green H, Bonneil E, Raposo G, Thibault P, Borgne RL, Vincent JP."
Journal name Traffic
Publication year 2012
Sample Drosophila S2 cells
Sample name Normal-Drosophila S2 tub-Wg
Isolation/purification methods Filtration
Ultracentrifugation
Sucrose density gradient
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
 Protein-protein interactions for Stam
  Protein Interactor ExoCarta ID Identification method PubMed Species
1 Irbp  
Two-hybrid Drosophila melanogaster
2 Mcm5  
Two-hybrid Drosophila melanogaster
3 CycJ  
Two-hybrid Drosophila melanogaster
4 dap  
Two-hybrid Drosophila melanogaster
5 Sirt4  
Two-hybrid Drosophila melanogaster
6 IntS8  
Two-hybrid Drosophila melanogaster
7 ct  
Affinity Capture-MS Drosophila melanogaster
8 CG8128  
Two-hybrid Drosophila melanogaster
9 CG9248  
Two-hybrid Drosophila melanogaster
10 inaD  
Two-hybrid Drosophila melanogaster
11 rev7  
Two-hybrid Drosophila melanogaster
12 CycG  
Two-hybrid Drosophila melanogaster
13 Fmr1  
Two-hybrid Drosophila melanogaster
14 plu  
Two-hybrid Drosophila melanogaster
15 CG11350  
Two-hybrid Drosophila melanogaster
16 pie  
Two-hybrid Drosophila melanogaster
17 sxc  
Two-hybrid Drosophila melanogaster
18 CG44009  
Two-hybrid Drosophila melanogaster
19 Pkc98E  
Two-hybrid Drosophila melanogaster
20 CG11286  
Two-hybrid Drosophila melanogaster
21 CG1368  
Two-hybrid Drosophila melanogaster
22 FANCI  
Two-hybrid Drosophila melanogaster
23 mr  
Two-hybrid Drosophila melanogaster
24 Hip1  
Two-hybrid Drosophila melanogaster
25 CG4586  
Two-hybrid Drosophila melanogaster
26 Pallidin  
Two-hybrid Drosophila melanogaster
27 Hrs  
Two-hybrid Drosophila melanogaster
Two-hybrid Drosophila melanogaster
28 LpR1  
Two-hybrid Drosophila melanogaster
29 Ndc80  
Two-hybrid Drosophila melanogaster
30 ASPP  
Two-hybrid Drosophila melanogaster
31 CG18754  
Two-hybrid Drosophila melanogaster
View the network image/svg+xml
 Pathways in which Stam is involved
No pathways found





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