Gene description for Gapdh1
Gene name Glyceraldehyde 3 phosphate dehydrogenase 1
Gene symbol Gapdh1
Other names/aliases BEST:GH12586
CG12055
DmelCG12055
GA3PDH
GADPH
GAP
GAPDH
GAPDH I
GAPDH-1
GAPDH1
GAPDHI
Gapd
Gapdh
Gapdh-1
Gapdh43E
gapdh
gapdh-1
gh12586
Species Drosophila melanogaster
 Database cross references - Gapdh1
ExoCarta ExoCarta_35728
Entrez Gene 35728
UniProt P07486  
 Gapdh1 identified in exosomes derived from the following tissue/cell type
Drosophila S2 cells 23035643    
 Gene ontology annotations for Gapdh1
Molecular Function
    NADP binding GO:0050661 IEA
    glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity GO:0004365 NAS
    NAD binding GO:0051287 IEA
Biological Process
    myoblast fusion GO:0007520 IMP
    somatic muscle development GO:0007525 IMP
    glucose metabolic process GO:0006006 IEA
    glycolytic process GO:0006096 NAS
    oxidation-reduction process GO:0055114 IEA
Subcellular Localization
    M band GO:0031430 IDA
    Z disc GO:0030018 IDA
    cytoplasm GO:0005737 NAS
    lipid particle GO:0005811 IDA
 Experiment description of studies that identified Gapdh1 in exosomes
1
Experiment ID 202
ISEV standards
✔
IEM
EV Biophysical techniques
✔
TSG10|RAB35
EV Cytosolic markers
✔
FLOT2
EV Membrane markers
✘ EV Negative markers
✘ EV Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 23035643    
Organism Drosophila melanogaster
Experiment description Drosophila S2 cells secrete Wingless on exosome-like vesicles but the Wingless gradient forms independently of exosomes.
Authors Beckett K, Monier S, Palmer L, Alexandre C, Green H, Bonneil E, Raposo G, Thibault P, Borgne RL, Vincent JP.
Journal name Traffic
Publication year 2012
Sample Drosophila S2 cells
Sample name Normal-Drosophila S2 tub-Wg
Isolation/purification methods Filtration
Ultracentrifugation
Sucrose density gradient
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
 Protein-protein interactions for Gapdh1
  Protein Interactor ExoCarta ID Identification method PubMed Species
No interactions are found.
 Pathways in which Gapdh1 is involved
PathwayEvidenceSource
Gluconeogenesis IEA Reactome
Glycolysis IEA Reactome





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