Gene description for Ggamma1
Gene name G protein gamma 1
Gene symbol Ggamma1
Other names/aliases CG8261
D-G[[gamma]]1
DmelCG8261
G[[gamma1]]
G[[gamma]]
Gbetagamma
Gg1
Ggamma
Ggamma-1
bro4
dg1alpha
l(2)k08017
Species Drosophila melanogaster
 Database cross references - Ggamma1
ExoCarta ExoCarta_35881
Entrez Gene 35881
UniProt P38040  
 Ggamma1 identified in exosomes derived from the following tissue/cell type
Drosophila S2 cells 23035643    
 Gene ontology annotations for Ggamma1
Molecular Function
    GTPase activity GO:0003924 NAS
    signal transducer activity GO:0004871 IEA
Biological Process
    heart process GO:0003015 IMP
    apical protein localization GO:0045176 TAS
    cell adhesion GO:0007155 IMP
    asymmetric neuroblast division GO:0055059 IMP
    cell adhesion involved in heart morphogenesis GO:0061343 IMP
    G-protein coupled receptor signaling pathway GO:0007186 NAS
    dorsal closure GO:0007391 IMP
    proboscis extension reflex GO:0007637 IMP
    embryonic heart tube development GO:0035050 IMP
    regulation of cell shape GO:0008360 IMP
    neurogenesis GO:0022008 IMP
    actin filament organization GO:0007015 IMP
Subcellular Localization
    heterotrimeric G-protein complex GO:0005834 NAS
    plasma membrane GO:0005886 IDA
 Experiment description of studies that identified Ggamma1 in exosomes
1
Experiment ID 202
ISEV standards
IEM
EV Biophysical techniques
TSG10|RAB35
EV Cytosolic markers
FLOT2
EV Membrane markers
EV Negative markers
EV Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 23035643    
Organism Drosophila melanogaster
Experiment description Drosophila S2 cells secrete Wingless on exosome-like vesicles but the Wingless gradient forms independently of exosomes.
Authors Beckett K, Monier S, Palmer L, Alexandre C, Green H, Bonneil E, Raposo G, Thibault P, Borgne RL, Vincent JP.
Journal name Traffic
Publication year 2012
Sample Drosophila S2 cells
Sample name Normal-Drosophila S2 tub-Wg
Isolation/purification methods Filtration
Ultracentrifugation
Sucrose density gradient
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
 Protein-protein interactions for Ggamma1
  Protein Interactor ExoCarta ID Identification method PubMed Species
No interactions are found.
 Pathways in which Ggamma1 is involved
No pathways found





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