Gene description for Pgi
Gene name Phosphoglucose isomerase
Gene symbol Pgi
Other names/aliases CG8251
DmelCG8251
GPI
Gpi
PGI
pgi
Species Drosophila melanogaster
 Database cross references - Pgi
ExoCarta ExoCarta_35886
Entrez Gene 35886
UniProt P52029  
 Pgi identified in exosomes derived from the following tissue/cell type
Drosophila S2 cells 23035643    
 Gene ontology annotations for Pgi
Molecular Function
    glucose-6-phosphate isomerase activity GO:0004347 NAS
    phosphogluconate dehydrogenase (decarboxylating) activity GO:0004616 ISS
Biological Process
    glycolytic process GO:0006096 NAS
    gluconeogenesis GO:0006094 NAS
Subcellular Localization
    cytoplasm GO:0005737 NAS
    lipid particle GO:0005811 IDA
 Experiment description of studies that identified Pgi in exosomes
1
Experiment ID 202
ISEV standards
✔
IEM
EV Biophysical techniques
✔
TSG10|RAB35
EV Cytosolic markers
✔
FLOT2
EV Membrane markers
✘ EV Negative markers
✘ EV Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 23035643    
Organism Drosophila melanogaster
Experiment description Drosophila S2 cells secrete Wingless on exosome-like vesicles but the Wingless gradient forms independently of exosomes.
Authors Beckett K, Monier S, Palmer L, Alexandre C, Green H, Bonneil E, Raposo G, Thibault P, Borgne RL, Vincent JP.
Journal name Traffic
Publication year 2012
Sample Drosophila S2 cells
Sample name Normal-Drosophila S2 tub-Wg
Isolation/purification methods Filtration
Ultracentrifugation
Sucrose density gradient
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
 Protein-protein interactions for Pgi
  Protein Interactor ExoCarta ID Identification method PubMed Species
No interactions are found.
 Pathways in which Pgi is involved
PathwayEvidenceSource
Gluconeogenesis IEA Reactome
Glycolysis IEA Reactome
TP53 Regulates Metabolic Genes IEA Reactome





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