Gene description for Slc47a1
Gene name solute carrier family 47 (multidrug and toxin extrusion), member 1
Gene symbol Slc47a1
Other names/aliases MATE1
RGD1311123
Species Rattus norvegicus
 Database cross references - Slc47a1
ExoCarta ExoCarta_360539
Entrez Gene 360539
UniProt Q5I0E9  
 Slc47a1 identified in exosomes derived from the following tissue/cell type
Urine 20535238    
 Gene ontology annotations for Slc47a1
Molecular Function
    drug transmembrane transporter activity GO:0015238 IDA
    monovalent cation:proton antiporter activity GO:0005451 IMP
Biological Process
    drug transport GO:0015893 IDA
    drug transmembrane transport GO:0006855 IDA
    hydrogen ion transmembrane transport GO:1902600 IMP
    organic cation transport GO:0015695 IDA
Subcellular Localization
    membrane-bounded vesicle GO:0031988 IDA
    integral component of membrane GO:0016021 IEA
    plasma membrane GO:0005886 IEA
 Experiment description of studies that identified Slc47a1 in exosomes
1
Experiment ID 192
ISEV standards
✔
CEM
EV Biophysical techniques
✔
TSG101|HSP70
EV Cytosolic markers
✔
CD63|CD81|FLOT
EV Membrane markers
✘ EV Negative markers
✘ EV Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 20535238    
Organism Rattus norvegicus
Experiment description Candidate biomarkers in exosome-like vesicles purified from rat and mouse urine samples.
Authors Conde-Vancells J, Rodriguez-Suarez E, Gonzalez E, Berisa A, Gil D, Embade N, Valle M, Luka Z, Elortza F, Wagner C, Lu SC, Mato JM, Falcon-Perez M.
Journal name Proteomics Clin Appl
Publication year 2010
Sample Urine
Sample name Urine - Rats of liver injury
Isolation/purification methods Differential centrifugation
Filtration
UltracentrifugationSucrose cushion
Sucrose density gradient
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
 Protein-protein interactions for Slc47a1
  Protein Interactor ExoCarta ID Identification method PubMed Species
No interactions are found.



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