Gene description for Vasp
Gene name vasodilator-stimulated phosphoprotein
Gene symbol Vasp
Other names/aliases -
Species Rattus norvegicus
 Database cross references - Vasp
ExoCarta ExoCarta_361517
Entrez Gene 361517
 Vasp identified in exosomes derived from the following tissue/cell type
Reticulocytes 21828046    
 Gene ontology annotations for Vasp
Molecular Function
    profilin binding GO:0005522 ISO
    SH3 domain binding GO:0017124 IEA
    actin binding GO:0003779 IEA
Biological Process
    actin polymerization or depolymerization GO:0008154 IEA
    actin cytoskeleton organization GO:0030036 ISO
    protein homotetramerization GO:0051289 IEA
    axon guidance GO:0007411 ISO
    neural tube closure GO:0001843 ISO
    positive regulation of actin filament polymerization GO:0030838 ISO
Subcellular Localization
    plasma membrane GO:0005886 ISO
    filopodium GO:0030175 ISO
    cytoskeleton GO:0005856 IEA
    cytoplasm GO:0005737 ISO
    focal adhesion GO:0005925 ISO
    lamellipodium GO:0030027 ISO
    extracellular exosome GO:0070062 ISO
 Experiment description of studies that identified Vasp in exosomes
1
Experiment ID 96
ISEV standards
EM
EV Biophysical techniques
TSG101|HSP90|HSC70
EV Cytosolic markers
MHCI
EV Membrane markers
EV Negative markers
EV Particle analysis
Identified molecule protein
Identification method Mass spectrometry [Orbitrap]
PubMed ID 21828046    
Organism Rattus norvegicus
Experiment description The proteo-lipidic composition of exosomes changes during reticulocyte maturation.
Authors Carayon K, Chaoui K, Ronzier E, Lazar I, Bertrand-Michel J, Roques V, Balor S, Terce F, Lopez A, Salome L, Joly E.
Journal name JBC
Publication year 2011
Sample Reticulocytes
Sample name Reticulocytes - D2 Rep 2
Isolation/purification methods Differential centrifugation
Ultracentrifugation
Sucrose density gradient
Flotation density 1.16-1.21 g/mL
Molecules identified in the study Protein
Lipids
Methods used in the study Mass spectrometry [QSTAR]
Mass spectrometry [Orbitrap]
Western blotting
 Protein-protein interactions for Vasp
  Protein Interactor ExoCarta ID Identification method PubMed Species
No interactions are found.
 Pathways in which Vasp is involved
No pathways found





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