Gene description for Vasp
Gene name vasodilator-stimulated phosphoprotein
Gene symbol Vasp
Other names/aliases -
Species Rattus norvegicus
 Database cross references - Vasp
ExoCarta ExoCarta_361517
Vesiclepedia VP_361517
Entrez Gene 361517
 Vasp identified in sEVs derived from the following tissue/cell type
Reticulocytes 21828046    
 Gene ontology annotations for Vasp
Molecular Function
    actin binding GO:0003779 IEA
    profilin binding GO:0005522 IBA
    profilin binding GO:0005522 ISO
    SH3 domain binding GO:0017124 IEA
Biological Process
    neural tube closure GO:0001843 IBA
    neural tube closure GO:0001843 ISO
    axon guidance GO:0007411 IBA
    axon guidance GO:0007411 ISO
    actin polymerization or depolymerization GO:0008154 IBA
    actin cytoskeleton organization GO:0030036 ISO
    positive regulation of actin filament polymerization GO:0030838 IBA
    positive regulation of actin filament polymerization GO:0030838 ISO
    protein homotetramerization GO:0051289 IEA
Subcellular Localization
    cytoplasm GO:0005737 IEA
    cytosol GO:0005829 IEA
    cytosol GO:0005829 ISO
    cytoskeleton GO:0005856 IEA
    plasma membrane GO:0005886 IBA
    plasma membrane GO:0005886 ISO
    focal adhesion GO:0005925 IBA
    focal adhesion GO:0005925 ISO
    lamellipodium GO:0030027 ISO
    filopodium GO:0030175 ISO
    postsynapse GO:0098794 IDA
    postsynapse GO:0098794 IMP
    glutamatergic synapse GO:0098978 IDA
    glutamatergic synapse GO:0098978 IMP
 Experiment description of studies that identified Vasp in sEVs
1
Experiment ID 96
MISEV standards
EM
Biophysical techniques
TSG101|HSP90|HSC70|MHCI
Enriched markers
Negative markers
Particle analysis
Identified molecule protein
Identification method Mass spectrometry [Orbitrap]
PubMed ID 21828046    
Organism Rattus norvegicus
Experiment description The proteo-lipidic composition of exosomes changes during reticulocyte maturation.
Authors "Carayon K, Chaoui K, Ronzier E, Lazar I, Bertrand-Michel J, Roques V, Balor S, Terce F, Lopez A, Salome L, Joly E."
Journal name JBC
Publication year 2011
Sample Reticulocytes
Sample name Reticulocytes - D2 Rep 2
Isolation/purification methods Differential centrifugation
Ultracentrifugation
Sucrose density gradient
Flotation density 1.16-1.21 g/mL
Molecules identified in the study Protein
Lipids
Methods used in the study Mass spectrometry [QSTAR]
Mass spectrometry [Orbitrap]
Western blotting
 Protein-protein interactions for Vasp
  Protein Interactor ExoCarta ID Identification method PubMed Species
No interactions are found.
 Pathways in which Vasp is involved
No pathways found





Perform bioinformatics analysis of your extracellular vesicle data set using FunRich, a open access standalone tool. NEW UPDATED VERSION OF FunRich available for download (12/09/2016) from here