Gene description for Rras
Gene name related RAS viral (r-ras) oncogene homolog
Gene symbol Rras
Other names/aliases p23
Species Rattus norvegicus
 Database cross references - Rras
ExoCarta ExoCarta_361568
Vesiclepedia VP_361568
Entrez Gene 361568
UniProt D3Z8L7  
 Rras identified in sEVs derived from the following tissue/cell type
Adipocytes 25998041    
 Gene ontology annotations for Rras
Molecular Function
    GTPase activity GO:0003924 IBA
    GTPase activity GO:0003924 ISO
    protein binding GO:0005515 IPI
    GTP binding GO:0005525 IBA
    GDP binding GO:0019003 IBA
    GDP binding GO:0019003 ISO
    protein-containing complex binding GO:0044877 ISO
Biological Process
    leukocyte differentiation GO:0002521 ISO
    signal transduction GO:0007165 IEA
    positive regulation of endothelial cell migration GO:0010595 ISO
    cell migration GO:0016477 ISO
    Schwann cell migration GO:0036135 ISO
    positive regulation of angiogenesis GO:0045766 ISO
    positive regulation of angiogenesis GO:0045766 ISS
    regulation of phosphatidylinositol 3-kinase/protein kinase B signal transduction GO:0051896 ISO
    face morphogenesis GO:0060325 ISO
    regulation of ERK1 and ERK2 cascade GO:0070372 ISO
    negative regulation of Schwann cell migration GO:1900148 ISO
    positive regulation of endothelial cell-matrix adhesion via fibronectin GO:1904906 ISO
    positive regulation of vasculogenesis GO:2001214 ISO
Subcellular Localization
    plasma membrane GO:0005886 IBA
 Experiment description of studies that identified Rras in sEVs
1
Experiment ID 225
MISEV standards
EM
Biophysical techniques
GAPDH|CD63
Enriched markers
Negative markers
NTA
Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 25998041    
Organism Rattus norvegicus
Experiment description Proteomic Analysis of Extracellular Vesicles Released by Adipocytes of Otsuka Long-Evans Tokushima Fatty (OLETF) Rats.
Authors "Lee JE, Moon PG, Lee IK, Baek MC"
Journal name Protein J
Publication year 2015
Sample Adipocytes
Sample name Adipocytes
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
Western blotting
 Protein-protein interactions for Rras
  Protein Interactor ExoCarta ID Identification method PubMed Species
No interactions are found.



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