Gene description for Atxn2l
Gene name ataxin 2-like
Gene symbol Atxn2l
Other names/aliases RGD1565868
Species Rattus norvegicus
 Database cross references - Atxn2l
ExoCarta ExoCarta_361649
Vesiclepedia VP_361649
Entrez Gene 361649
 Atxn2l identified in sEVs derived from the following tissue/cell type
Reticulocytes 21828046    
 Gene ontology annotations for Atxn2l
Molecular Function
    mRNA binding GO:0003729 IBA
Biological Process
    biological_process GO:0008150 ND
    mRNA metabolic process GO:0016071 ISO
    stress granule assembly GO:0034063 IBA
Subcellular Localization
    cytosol GO:0005829 IEA
    cytosol GO:0005829 ISO
    cytoplasmic stress granule GO:0010494 IBA
    cytoplasmic stress granule GO:0010494 ISO
    membrane GO:0016020 ISO
    nuclear speck GO:0016607 ISO
 Experiment description of studies that identified Atxn2l in sEVs
1
Experiment ID 94
MISEV standards
Biophysical techniques
Enriched markers
Negative markers
Particle analysis
Identified molecule protein
Identification method Mass spectrometry [Orbitrap]
PubMed ID 21828046    
Organism Rattus norvegicus
Experiment description The proteo-lipidic composition of exosomes changes during reticulocyte maturation.
Authors "Carayon K, Chaoui K, Ronzier E, Lazar I, Bertrand-Michel J, Roques V, Balor S, Terce F, Lopez A, Salome L, Joly E."
Journal name JBC
Publication year 2011
Sample Reticulocytes
Sample name Reticulocytes - D4 Rep 1
Isolation/purification methods Differential centrifugation
Ultracentrifugation
Sucrose density gradient
Flotation density 1.16-1.21 g/mL
Molecules identified in the study Protein
Lipids
Methods used in the study Mass spectrometry [QSTAR]
Mass spectrometry [Orbitrap]
Western blotting
 Protein-protein interactions for Atxn2l
  Protein Interactor ExoCarta ID Identification method PubMed Species
1 Slc8a1  
Affinity Capture-MS Rattus norvegicus
2 Slc8a1  
Reconstituted Complex Mus musculus
View the network image/svg+xml
 Pathways in which Atxn2l is involved
No pathways found





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