Gene description for Atxn2l
Gene name ataxin 2-like
Gene symbol Atxn2l
Other names/aliases RGD1565868
Species Rattus norvegicus
 Database cross references - Atxn2l
ExoCarta ExoCarta_361649
Entrez Gene 361649
 Atxn2l identified in exosomes derived from the following tissue/cell type
Reticulocytes 21828046    
 Gene ontology annotations for Atxn2l
Molecular Function
    poly(A) RNA binding GO:0044822 ISO
    molecular_function GO:0003674 ND
Biological Process
    biological_process GO:0008150 ND
    regulation of cytoplasmic mRNA processing body assembly GO:0010603 ISO
    stress granule assembly GO:0034063 ISO
Subcellular Localization
    nuclear speck GO:0016607 ISO
    cytoplasmic stress granule GO:0010494 ISO
    cellular_component GO:0005575 ND
    membrane GO:0016020 ISO
    cytoplasm GO:0005737 ISO
 Experiment description of studies that identified Atxn2l in exosomes
1
Experiment ID 94
ISEV standards
EM
EV Biophysical techniques
TSG101|HSP90|HSC70
EV Cytosolic markers
MHCI
EV Membrane markers
EV Negative markers
EV Particle analysis
Identified molecule protein
Identification method Mass spectrometry [Orbitrap]
PubMed ID 21828046    
Organism Rattus norvegicus
Experiment description The proteo-lipidic composition of exosomes changes during reticulocyte maturation.
Authors Carayon K, Chaoui K, Ronzier E, Lazar I, Bertrand-Michel J, Roques V, Balor S, Terce F, Lopez A, Salome L, Joly E.
Journal name JBC
Publication year 2011
Sample Reticulocytes
Sample name Reticulocytes - D4 Rep 1
Isolation/purification methods Differential centrifugation
Ultracentrifugation
Sucrose density gradient
Flotation density 1.16-1.21 g/mL
Molecules identified in the study Protein
Lipids
Methods used in the study Mass spectrometry [QSTAR]
Mass spectrometry [Orbitrap]
Western blotting
 Protein-protein interactions for Atxn2l
  Protein Interactor ExoCarta ID Identification method PubMed Species
No interactions are found.
 Pathways in which Atxn2l is involved
No pathways found





Perform bioinformatics analysis of your extracellular vesicle data set using FunRich, a open access standalone tool. NEW UPDATED VERSION OF FunRich available for download (12/09/2016) from here