Gene description for Tmem109
Gene name transmembrane protein 109
Gene symbol Tmem109
Other names/aliases -
Species Rattus norvegicus
 Database cross references - Tmem109
ExoCarta ExoCarta_361732
Entrez Gene 361732
UniProt Q6AYQ4  
 Tmem109 identified in exosomes derived from the following tissue/cell type
Adipocytes 25998041    
 Gene ontology annotations for Tmem109
Molecular Function
    molecular_function GO:0003674 ND
Biological Process
    cellular response to gamma radiation GO:0071480 ISO
    biological_process GO:0008150 ND
    negative regulation of cell death GO:0060548 ISO
    intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator GO:0042771 ISO
Subcellular Localization
    extracellular exosome GO:0070062 ISO
    nuclear outer membrane GO:0005640 IEA
    sarcoplasmic reticulum membrane GO:0033017 IEA
    integral component of membrane GO:0016021 IEA
    cellular_component GO:0005575 ND
    intracellular GO:0005622 ISO
 Experiment description of studies that identified Tmem109 in exosomes
1
Experiment ID 225
ISEV standards
✔
EM
EV Biophysical techniques
✔
GAPDH
EV Cytosolic markers
✔
CD63
EV Membrane markers
✘ EV Negative markers
✔
NTA
EV Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 25998041    
Organism Rattus norvegicus
Experiment description Proteomic Analysis of Extracellular Vesicles Released by Adipocytes of Otsuka Long-Evans Tokushima Fatty (OLETF) Rats.
Authors Lee JE, Moon PG, Lee IK, Baek MC
Journal name Protein J
Publication year 2015
Sample Adipocytes
Sample name Adipocytes
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
Western blotting
 Protein-protein interactions for Tmem109
  Protein Interactor ExoCarta ID Identification method PubMed Species
No interactions are found.
 Pathways in which Tmem109 is involved
No pathways found





Perform bioinformatics analysis of your extracellular vesicle data set using FunRich, a open access standalone tool. NEW UPDATED VERSION OF FunRich available for download (12/09/2016) from here