Gene description for Aifm2
Gene name apoptosis-inducing factor, mitochondrion-associated 2
Gene symbol Aifm2
Other names/aliases Amid
Prg3
Species Rattus norvegicus
 Database cross references - Aifm2
ExoCarta ExoCarta_361843
Entrez Gene 361843
 Aifm2 identified in exosomes derived from the following tissue/cell type
Adipocytes 25998041    
 Gene ontology annotations for Aifm2
Molecular Function
    flavin adenine dinucleotide binding GO:0050660 ISO
    DNA binding GO:0003677 ISO
    NADH dehydrogenase (ubiquinone) activity GO:0008137 IBA
    electron-transferring-flavoprotein dehydrogenase activity GO:0004174 ISO
Biological Process
    positive regulation of apoptotic process GO:0043065 ISO
    oxidation-reduction process GO:0055114 IEA
    apoptotic mitochondrial changes GO:0008637 ISO
Subcellular Localization
    lipid particle GO:0005811 ISO
    mitochondrial outer membrane GO:0005741 ISO
    cytosol GO:0005829 ISO
    cytoplasm GO:0005737 ISO
    extracellular space GO:0005615 ISO
    mitochondrion GO:0005739 ISO
 Experiment description of studies that identified Aifm2 in exosomes
1
Experiment ID 225
ISEV standards
EM
EV Biophysical techniques
GAPDH
EV Cytosolic markers
CD63
EV Membrane markers
EV Negative markers
NTA
EV Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 25998041    
Organism Rattus norvegicus
Experiment description Proteomic Analysis of Extracellular Vesicles Released by Adipocytes of Otsuka Long-Evans Tokushima Fatty (OLETF) Rats.
Authors Lee JE, Moon PG, Lee IK, Baek MC
Journal name Protein J
Publication year 2015
Sample Adipocytes
Sample name Adipocytes
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
Western blotting
 Protein-protein interactions for Aifm2
  Protein Interactor ExoCarta ID Identification method PubMed Species
No interactions are found.
 Pathways in which Aifm2 is involved
No pathways found





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