Gene description for Vps26a
Gene name vacuolar protein sorting 26 homolog A (S. pombe)
Gene symbol Vps26a
Other names/aliases Vps26
Species Rattus norvegicus
 Database cross references - Vps26a
ExoCarta ExoCarta_361846
Vesiclepedia VP_361846
Entrez Gene 361846
UniProt Q6AY86  
 Vps26a identified in sEVs derived from the following tissue/cell type
Reticulocytes 21828046    
 Gene ontology annotations for Vps26a
Biological Process
    intracellular protein transport GO:0006886 IBA
    intracellular protein transport GO:0006886 IEA
    biological_process GO:0008150 ND
    endocytic recycling GO:0032456 IEA
    endocytic recycling GO:0032456 ISO
    endocytic recycling GO:0032456 ISS
    retrograde transport, endosome to Golgi GO:0042147 IBA
    retrograde transport, endosome to Golgi GO:0042147 IEA
    retrograde transport, endosome to Golgi GO:0042147 ISO
    retrograde transport, endosome to Golgi GO:0042147 ISO
    retrograde transport, endosome to Golgi GO:0042147 ISS
Subcellular Localization
    lysosome GO:0005764 IEA
    lysosome GO:0005764 ISO
    endosome GO:0005768 IBA
    endosome GO:0005768 ISO
    endosome GO:0005768 ISS
    early endosome GO:0005769 IEA
    early endosome GO:0005769 ISO
    early endosome GO:0005769 ISS
    cytosol GO:0005829 IDA
    cytosol GO:0005829 IEA
    endosome membrane GO:0010008 IEA
    endosome membrane GO:0010008 ISO
    retromer complex GO:0030904 IBA
    retromer complex GO:0030904 IDA
    retromer complex GO:0030904 ISO
    retromer, cargo-selective complex GO:0030906 IEA
    retromer, cargo-selective complex GO:0030906 ISO
    vesicle GO:0031982 ISO
    vesicle GO:0031982 ISS
    tubular endosome GO:0097422 IEA
    tubular endosome GO:0097422 ISO
    tubular endosome GO:0097422 ISS
 Experiment description of studies that identified Vps26a in sEVs
1
Experiment ID 90
MISEV standards
EM
Biophysical techniques
HSC70|HSP90|TSG101|MHCI
Enriched markers
Negative markers
Particle analysis
Identified molecule protein
Identification method Mass spectrometry [Orbitrap]
PubMed ID 21828046    
Organism Rattus norvegicus
Experiment description The proteo-lipidic composition of exosomes changes during reticulocyte maturation.
Authors "Carayon K, Chaoui K, Ronzier E, Lazar I, Bertrand-Michel J, Roques V, Balor S, Terce F, Lopez A, Salome L, Joly E"
Journal name JBC
Publication year 2011
Sample Reticulocytes
Sample name Reticulocytes - D2 Rep 1
Isolation/purification methods Differential centrifugation
Ultracentrifugation
Sucrose density gradient
Flotation density 1.16-1.21 g/mL
Molecules identified in the study Protein
Lipids
Methods used in the study Mass spectrometry [QSTAR]
Mass spectrometry [Orbitrap]
Western blotting
 Protein-protein interactions for Vps26a
  Protein Interactor ExoCarta ID Identification method PubMed Species
No interactions are found.
 Pathways in which Vps26a is involved
PathwayEvidenceSource
Signal Transduction IEA Reactome
Signaling by WNT IEA Reactome
WNT ligand biogenesis and trafficking IEA Reactome





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