Gene description for Vps26a
Gene name vacuolar protein sorting 26 homolog A (S. pombe)
Gene symbol Vps26a
Other names/aliases Vps26
Species Rattus norvegicus
 Database cross references - Vps26a
ExoCarta ExoCarta_361846
Entrez Gene 361846
UniProt Q6AY86  
 Vps26a identified in exosomes derived from the following tissue/cell type
Reticulocytes 21828046    
 Gene ontology annotations for Vps26a
Molecular Function
    protein transporter activity GO:0008565 IBA
Biological Process
    retrograde transport, endosome to Golgi GO:0042147 ISS
    intracellular protein transport GO:0006886 IBA
    retrograde transport, endosome to plasma membrane GO:1990126 ISS
Subcellular Localization
    intracellular membrane-bounded organelle GO:0043231 ISO
    cytosol GO:0005829 ISO
    extracellular exosome GO:0070062 ISO
    tubular endosome GO:0097422 ISS
    endosome GO:0005768 ISS
    early endosome GO:0005769 ISS
    vesicle GO:0031982 ISS
    retromer complex GO:0030904 ISO
    endosome membrane GO:0010008 IEA
 Experiment description of studies that identified Vps26a in exosomes
1
Experiment ID 90
ISEV standards
EM
EV Biophysical techniques
HSC70|HSP90|TSG101
EV Cytosolic markers
MHCI
EV Membrane markers
EV Negative markers
EV Particle analysis
Identified molecule protein
Identification method Mass spectrometry [Orbitrap]
PubMed ID 21828046    
Organism Rattus norvegicus
Experiment description The proteo-lipidic composition of exosomes changes during reticulocyte maturation.
Authors Carayon K, Chaoui K, Ronzier E, Lazar I, Bertrand-Michel J, Roques V, Balor S, Terce F, Lopez A, Salome L, Joly E
Journal name JBC
Publication year 2011
Sample Reticulocytes
Sample name Reticulocytes - D2 Rep 1
Isolation/purification methods Differential centrifugation
Ultracentrifugation
Sucrose density gradient
Flotation density 1.16-1.21 g/mL
Molecules identified in the study Protein
Lipids
Methods used in the study Mass spectrometry [QSTAR]
Mass spectrometry [Orbitrap]
Western blotting
 Protein-protein interactions for Vps26a
  Protein Interactor ExoCarta ID Identification method PubMed Species
No interactions are found.
 Pathways in which Vps26a is involved
PathwayEvidenceSource
WNT ligand biogenesis and trafficking IEA Reactome





Perform bioinformatics analysis of your extracellular vesicle data set using FunRich, a open access standalone tool. NEW UPDATED VERSION OF FunRich available for download (12/09/2016) from here