Gene description for Postn
Gene name periostin, osteoblast specific factor
Gene symbol Postn
Other names/aliases Plf
Species Rattus norvegicus
 Database cross references - Postn
ExoCarta ExoCarta_361945
Vesiclepedia VP_361945
Entrez Gene 361945
 Postn identified in sEVs derived from the following tissue/cell type
Reticulocytes 21828046    
 Gene ontology annotations for Postn
Molecular Function
    protein binding GO:0005515 IPI
    heparin binding GO:0008201 ISO
    metal ion binding GO:0046872 ISO
    cell adhesion molecule binding GO:0050839 IBA
Biological Process
    response to hypoxia GO:0001666 IEP
    negative regulation of cell-matrix adhesion GO:0001953 IDA
    regulation of systemic arterial blood pressure GO:0003073 IDA
    cell adhesion GO:0007155 IBA
    cell adhesion GO:0007155 ISO
    regulation of Notch signaling pathway GO:0008593 ISO
    response to mechanical stimulus GO:0009612 IEP
    tissue development GO:0009888 ISO
    response to muscle activity GO:0014850 IEP
    positive regulation of smooth muscle cell migration GO:0014911 IMP
    extracellular matrix organization GO:0030198 IBA
    extracellular matrix organization GO:0030198 ISO
    response to estradiol GO:0032355 IEP
    cellular response to fibroblast growth factor stimulus GO:0044344 IEP
    cellular response to vitamin K GO:0071307 ISO
    cellular response to tumor necrosis factor GO:0071356 IEP
    cellular response to transforming growth factor beta stimulus GO:0071560 IEP
    negative regulation of substrate adhesion-dependent cell spreading GO:1900025 IDA
    neuron projection extension GO:1990138 IMP
    bone regeneration GO:1990523 IEP
    positive regulation of chemokine (C-X-C motif) ligand 2 production GO:2000343 IMP
Subcellular Localization
    extracellular space GO:0005615 IBA
    extracellular space GO:0005615 IDA
    trans-Golgi network GO:0005802 ISO
    extracellular matrix GO:0031012 IBA
    extracellular matrix GO:0031012 ISO
    neuromuscular junction GO:0031594 IDA
    collagen-containing extracellular matrix GO:0062023 ISO
 Experiment description of studies that identified Postn in sEVs
1
Experiment ID 98
MISEV standards
✔
EM
Biophysical techniques
✔
TSG101|HSP90|HSC70|MHCI
Enriched markers
✘ Negative markers
✘ Particle analysis
Identified molecule protein
Identification method Mass spectrometry [Orbitrap]
PubMed ID 21828046    
Organism Rattus norvegicus
Experiment description The proteo-lipidic composition of exosomes changes during reticulocyte maturation.
Authors "Carayon K, Chaoui K, Ronzier E, Lazar I, Bertrand-Michel J, Roques V, Balor S, Terce F, Lopez A, Salome L, Joly E."
Journal name JBC
Publication year 2011
Sample Reticulocytes
Sample name Reticulocytes - D7 Rep 2
Isolation/purification methods Differential centrifugation
Ultracentrifugation
Sucrose density gradient
Flotation density 1.13-1.25 g/mL
Molecules identified in the study Protein
Lipids
Methods used in the study Mass spectrometry [QSTAR]
Mass spectrometry [Orbitrap]
Western blotting
 Protein-protein interactions for Postn
  Protein Interactor ExoCarta ID Identification method PubMed Species
No interactions are found.
 Pathways in which Postn is involved
No pathways found





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