Gene description for Agl
Gene name amylo-alpha-1, 6-glucosidase, 4-alpha-glucanotransferase
Gene symbol Agl
Other names/aliases -
Species Rattus norvegicus
 Database cross references - Agl
ExoCarta ExoCarta_362029
Vesiclepedia VP_362029
Entrez Gene 362029
 Agl identified in sEVs derived from the following tissue/cell type
Reticulocytes 21828046    
 Gene ontology annotations for Agl
Molecular Function
    glycogen debranching enzyme activity GO:0004133 ISO
    4-alpha-glucanotransferase activity GO:0004134 IBA
    4-alpha-glucanotransferase activity GO:0004134 IDA
    4-alpha-glucanotransferase activity GO:0004134 ISO
    amylo-alpha-1,6-glucosidase activity GO:0004135 IBA
    amylo-alpha-1,6-glucosidase activity GO:0004135 IDA
    amylo-alpha-1,6-glucosidase activity GO:0004135 ISO
    carbohydrate binding GO:0030246 IDA
    polysaccharide binding GO:0030247 ISO
    polyubiquitin modification-dependent protein binding GO:0031593 ISO
Biological Process
    glycogen metabolic process GO:0005977 ISO
    glycogen biosynthetic process GO:0005978 IEA
    glycogen catabolic process GO:0005980 IBA
    glycogen catabolic process GO:0005980 IDA
    glycogen catabolic process GO:0005980 IMP
    glycogen catabolic process GO:0005980 ISO
    response to nutrient GO:0007584 IDA
    response to hormone GO:0009725 IDA
    response to glucocorticoid GO:0051384 IDA
Subcellular Localization
    nucleus GO:0005634 ISO
    cytoplasm GO:0005737 ISO
    cytosol GO:0005829 ISO
    inclusion body GO:0016234 ISO
    sarcoplasmic reticulum GO:0016529 IDA
 Experiment description of studies that identified Agl in sEVs
1
Experiment ID 98
MISEV standards
EM
Biophysical techniques
TSG101|HSP90|HSC70|MHCI
Enriched markers
Negative markers
Particle analysis
Identified molecule protein
Identification method Mass spectrometry [Orbitrap]
PubMed ID 21828046    
Organism Rattus norvegicus
Experiment description The proteo-lipidic composition of exosomes changes during reticulocyte maturation.
Authors "Carayon K, Chaoui K, Ronzier E, Lazar I, Bertrand-Michel J, Roques V, Balor S, Terce F, Lopez A, Salome L, Joly E."
Journal name JBC
Publication year 2011
Sample Reticulocytes
Sample name Reticulocytes - D7 Rep 2
Isolation/purification methods Differential centrifugation
Ultracentrifugation
Sucrose density gradient
Flotation density 1.13-1.25 g/mL
Molecules identified in the study Protein
Lipids
Methods used in the study Mass spectrometry [QSTAR]
Mass spectrometry [Orbitrap]
Western blotting
 Protein-protein interactions for Agl
  Protein Interactor ExoCarta ID Identification method PubMed Species
No interactions are found.
 Pathways in which Agl is involved
No pathways found





Perform bioinformatics analysis of your extracellular vesicle data set using FunRich, a open access standalone tool. NEW UPDATED VERSION OF FunRich available for download (12/09/2016) from here