Gene description for Agl
Gene name amylo-alpha-1, 6-glucosidase, 4-alpha-glucanotransferase
Gene symbol Agl
Other names/aliases -
Species Rattus norvegicus
 Database cross references - Agl
ExoCarta ExoCarta_362029
Entrez Gene 362029
 Agl identified in exosomes derived from the following tissue/cell type
Reticulocytes 21828046    
 Gene ontology annotations for Agl
Molecular Function
    polyubiquitin binding GO:0031593 ISO
    carbohydrate binding GO:0030246 IDA
    4-alpha-glucanotransferase activity GO:0004134 IMP
    glycogen debranching enzyme activity GO:0004133 ISO
    polysaccharide binding GO:0030247 ISO
    amylo-alpha-1,6-glucosidase activity GO:0004135 IMP
Biological Process
    response to hormone GO:0009725 IDA
    glycogen catabolic process GO:0005980 IMP
    response to glucocorticoid GO:0051384 IDA
    glycogen biosynthetic process GO:0005978 IEA
    response to nutrient GO:0007584 IDA
    glycogen metabolic process GO:0005977 ISO
Subcellular Localization
    inclusion body GO:0016234 ISO
    cytoplasm GO:0005737 ISO
    nucleoplasm GO:0005654 ISO
    nucleus GO:0005634 ISO
    sarcoplasmic reticulum GO:0016529 IDA
 Experiment description of studies that identified Agl in exosomes
1
Experiment ID 98
ISEV standards
EM
EV Biophysical techniques
TSG101|HSP90|HSC70
EV Cytosolic markers
MHCI
EV Membrane markers
EV Negative markers
EV Particle analysis
Identified molecule protein
Identification method Mass spectrometry [Orbitrap]
PubMed ID 21828046    
Organism Rattus norvegicus
Experiment description The proteo-lipidic composition of exosomes changes during reticulocyte maturation.
Authors Carayon K, Chaoui K, Ronzier E, Lazar I, Bertrand-Michel J, Roques V, Balor S, Terce F, Lopez A, Salome L, Joly E.
Journal name JBC
Publication year 2011
Sample Reticulocytes
Sample name Reticulocytes - D7 Rep 2
Isolation/purification methods Differential centrifugation
Ultracentrifugation
Sucrose density gradient
Flotation density 1.13-1.25 g/mL
Molecules identified in the study Protein
Lipids
Methods used in the study Mass spectrometry [QSTAR]
Mass spectrometry [Orbitrap]
Western blotting
 Protein-protein interactions for Agl
  Protein Interactor ExoCarta ID Identification method PubMed Species
No interactions are found.
 Pathways in which Agl is involved
No pathways found





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